Results 101 to 110 of about 419,076 (339)

TWF2 Drives Tumor Progression and Sunitinib Resistance in Renal Cell Carcinoma through Hippo Signaling Suppression

Advanced Science, EarlyView.
Twinfilin actin‐binding protein (TWF2) is upregulated in sunitinib‐resistant renal cell carcinoma (RCC) cells, where it interacts with YAP and protects YAP from degradation. Stabilized YAP translocates into the nucleus and activates transcription of target genes, promoting RCC progression and drug resistance.
Liangmin Fu, Wuyuan Liao, Youyan Tan, Hansen Lin, Kun Ye, Xinwei Zhou, Mingjie Lin, Kangbo Huang, Minyu Chen, Jietao Wei, Haoqian Feng, Yuhang Chen, Jinwei Chen, Bohong Guan, Shan Li, Zhengkun Zhang, Anze Yu, Zihao Feng, Lizhen Zhang, Guannan Shu, Jun Lu, Wei Chen, Yihui Pan, Jiefeng Yang, Junhang Luo, Li Luo   +25 more
wiley   +1 more source

Expression and Function of Chemokines CXCL9-11 in Micturition Pathways in Cyclophosphamide (CYP)-Induced Cystitis and Somatic Sensitivity in Mice

Frontiers in Systems Neuroscience, 2018
Changes in urinary bladder function and somatic sensation may be mediated, in part, by inflammatory changes in the urinary bladder including the expression of chemokines. Male and female C57BL/6 mice were treated with cyclophosphamide (CYP; 75 mg/kg, 200
Michael Guo, Phat Chang, Eric Hauke, Beatrice M. Girard, Katharine Tooke, Jacqueline Ojala, Susan M. Malley, Harrison Hsiang, Margaret A. Vizzard   +8 more
doaj   +1 more source

Dnmt1 Alleviates S1PR1‐Mediated Pyroptosis after Spinal Cord Injury through Regulating Pon3 Expression

Advanced Science, EarlyView.
This study systematically explores the action mechanism of Pon3 and its regulatory targets in spinal cord injury (SCI). It demonstrates that Dnmt1 regulates Pon3 expression by modulating methylation levels, thereby inhibiting S1PR1‐mediated pyroptosis and improving SCI prognosis.
Birong Peng, Haolong Lin, Mi Zhang, Wenhao Kuang, Jiaqi Zhang, Shuai Wang, Yuanfang Sun, Wenning Xu, Lixin Zhu   +8 more
wiley   +1 more source

Inguinal Herniation of the Urinary Bladder Presenting as Recurrent Urinary Retention

Case Reports in Surgery, 2015
Herniation of the urinary bladder into the inguinal canal is an uncommon finding, observed in 0.5–4% of inguinal hernias (Curry (2000)). It is usually associated with other conditions that increase intra-abdominal pressure such as bladder neck ...
Amit Frenkel, Aviel Roy-Shapira, Ilan Shelef, Gadi Shaked, Evgeni Brotfain, Leonid Koyfman, Abraham Borer, Moti Klein   +7 more
doaj   +1 more source

A Randomized Controlled Trial of Device Guided, Slow-Paced Respiration in Women with Overactive Bladder Syndrome. [PDF]

, 2019
PurposeWe evaluated the effects of device guided, slow-paced respiration on urgency associated urinary symptoms, perceived stress and anxiety, and autonomic function in women with overactive bladder syndrome.Materials and methodsWe performed a randomized,
Grady, Deborah, Hernandez, Cesar, Huang, Alison J, Mendes, Wendy B, Schembri, Michael, Subak, Leslee L   +5 more
core   +1 more source

Single‐Cell Dissection of the Biological Function and Molecular Features Underlying the Micropeptide LSMEM1 in Kidney

Advanced Science, EarlyView.
LSMEM1, an evolutionarily conserved micropeptide with extreme hydrophobicity (aliphatic index═113) and dynamic amphiphilicity (GRAVY═0.017), features a strong α‐helical transmembrane anchor (residues 64‐86). Single‐cell analysis reveals its critical role in renal lipid homeostasis.
Peimin Liu, Hong Zhang, Shanzhi Yang, Jiaoqing Li, Danfeng Wu, Haosen Xu, Huan Jiang, Yi Jing, Guoxiang Jin, Ruobing Liu, Ning Fan, Xiaoyan Bai   +11 more
wiley   +1 more source

Bladder Calculus Causing Large Bowel Obstruction

The Annals of African Surgery, 2019
Urinary tract calculi are fairly common, though bladder calculi are less common, accounting for only 5% of urinary tract calculi. Bladder calculi, particularly large bladder calculi, are usually associated with pathology in the urinary tract.
Alessandro Bellomo, Morapedi Kwati, Jorge Monzon, Babatunde Ogunrombi   +3 more
doaj  

Understanding the role of mesenchymal stem cells in urinary bladder regeneration—a preclinical study on a porcine model

Stem Cell Research & Therapy, 2018
Background The tissue engineering of urinary bladder advances rapidly reflecting clinical need for a new kind of therapeutic solution for patients requiring urinary bladder replacement.
Marta Pokrywczynska, Arkadiusz Jundzill, Marta Rasmus, Jan Adamowicz, Daria Balcerczyk, Monika Buhl, Karolina Warda, Lukasz Buchholz, Maciej Gagat, Dariusz Grzanka, Tomasz Drewa   +10 more
doaj   +1 more source

The performance of the Xpert Bladder Cancer Monitor Test and voided urinary cytology in the follow-up of urinary bladder tumors

Radiology and Oncology, 2020
Cystoscopy in complement with urinary cytology represents the gold standard for the follow-up of patients with urinary bladder tumours. Xpert Bladder Cancer Monitor Test (XBC) is a novel mRNA-based urine test for bladder cancer surveillance.
Smrkolj Tomaz, Cegovnik Primozic Urska, Fabjan Teja, Sterpin Sasa, Osredkar Josko   +4 more
doaj   +1 more source

Conservative interventions for urinary incontinence in women: an overview of Cochrane systematic reviews [PDF]

, 2016
This is the protocol for a review and there is no abstract. The objectives are as follows:  To synthesise Cochrane reviews of conservative interventions, as described above, for the prevention or treatment of female urinary incontinence.Output Type ...
Alewijnse, Alewijnse, Alhasso, Alves, Amaro, Balshem, Bastian, Berkman, Blaivas, Bogner, Bump, Bø, Cadwell, Carriere, Chaimani, Chang, Chiarelli, Clement, Cody, Dean, Dumoulin, Duthie, Eustice, Ford, Francis, French, Glazener, Glazener, Godec, Groat, Groat, Groutz, Guyatt, Guyatt, Guyatt, Guyatt, Guyatt, Guyatt, Guyatt, Hajebrahimi, Haylen, Herbison, Hunskaar, Hunskaar, Imamura, Islah, Jackson, Kelleher, Kirchin, Komesu, Lapitan, Lipp, MacArthur, McClurg, Melville, Messelink, Milsom, Morrill, Morrison, Ostaszkiewicz, Ostaszkiewicz, Palmer, Perry, Pollock, Rai, Rehman, Sandvik, Sandweiss, Shinohara, Smith, Takahashi, Thom, Turner, Wagner, Wallace, Wang, Whitford, Wilks, Wilson, Yau   +79 more
core   +3 more sources