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Nano-Formulation Based Intravesical Drug Delivery Systems: An Overview of Versatile Approaches to Improve Urinary Bladder Diseases [PDF]
Pharmaceutics, 2022 Intravesical drug delivery is a direct drug delivery approach for the treatment of various bladder diseases. The human urinary bladder has distinctive anatomy, making it an effective barrier against any toxic agent seeking entry into the bloodstream ...
Muhammad Sarfraz +7 more
doaj +3 more sources
Urinary Microbiome in Bladder Diseases—Review
Biomedicines, 2023 The microbiome is the totality of microorganisms found in a specific biological niche. It has been proven that in the human body, the microbiome is responsible for its proper functioning.
Joanna Chorbińska +5 more
doaj +4 more sources
Prevalence and characteristics of bladder wall thickening in dogs without lower urinary tract disease: an ultrasonographic study [PDF]
Frontiers in Veterinary ScienceIntroductionAssessment of bladder wall thickness by ultrasound is influenced by bladder distension and body weight, complicating interpretation. In the author’s experience, cranial or cranio-ventral bladder wall thickening is commonly observed in dogs ...
Chloé François +5 more
doaj +4 more sources
Microbiome in urological diseases: Axis crosstalk and bladder disorders [PDF]
Investigative and Clinical Urology, 2023 Since the identification of the human urinary microbiome, numerous studies have characterized this microbial community and improved our knowledge of its association with urinary diseases.
Hae Woong Choi +2 more
doaj +2 more sources
Neurogenic Defects Occur in LRIG2-Associated Urinary Bladder Disease [PDF]
Kidney International Reports, 2023 Urofacial, or Ochoa, syndrome (UFS) is an autosomal recessive disease featuring a dyssynergic bladder with detrusor smooth muscle contracting against an undilated outflow tract. It also features an abnormal grimace. Half of individuals with UFS carry biallelic variants in HPSE2, whereas other rare families carry variants in LRIG2.LRIG2 is ...
Céline Grenier +11 more
openalex +6 more sources
Urinary Tract Infection in Overactive Bladder: An Update on Pathophysiological Mechanisms
Frontiers in Physiology, 2022 Overactive bladder (OAB) is a clinical syndrome defined by urinary urgency, increased daytime urinary frequency and/or nocturia, with or without urinary incontinence, that affects approximately 11% of the western population.
Kylie J. Mansfield +4 more
doaj +2 more sources
Rare and Aggressive Disease: Urinary Bladder Leiomyosarcoma [PDF]
Journal of Clinical MedicineBackground: Bladder leiomyosarcoma is an extremely rare non-urothelial malignancy, accounting for less than 0.1% of all bladder tumors. It presents significant diagnostic and therapeutic challenges due to its aggressive nature and the absence of standardized treatment protocols. Case presentation: We report the case of a 61-year-old woman who presented
Žilvinas Venclovas +6 more
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Urinary Bladder Dysfunction in Transgenic Sickle Cell Disease Mice
PLOS ONE, 2015 Urological complications associated with sickle cell disease (SCD), include nocturia, enuresis, urinary infections and urinary incontinence. However, scientific evidence to ascertain the underlying cause of the lower urinary tract symptoms in SCD is lacking.Thus, the aim of this study was to evaluate urinary function, in vivo and ex vivo, in the ...
Mário Angelo Claudino +10 more
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Urobiome: An outlook on the metagenome of urological diseases [PDF]
Investigative and Clinical Urology, 2021 The urinary tract likely plays a role in the development of various urinary diseases due to the recently recognized notion that urine is not sterile. In this mini review, we summarize the current literature regarding the urinary microbiome and mycobiome ...
Rachel Shoemaker, Jayoung Kim
doaj +1 more source
The Urinary Microbiome: A Pediatric Urological Perspective [PDF]
Urogenital Tract Infection, 2022 The human microbiome is currently being studied with increasing interest. The microbiome refers to the microorganisms living in the body and their genetic information.
Sang Don Lee, Jae Min Chung
doaj +1 more source