Results 101 to 110 of about 14,878 (254)

Harnessing Nature: Computational and Experimental Insights Into Ipomoea obscura Metabolites for Bladder Cancer Therapy

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Ipomoea obscura (L.), a medicinal plant from the Convolvulaceae family, has been traditionally used to treat various ailments. This study evaluated the in vitro cytotoxicity of its ethanolic leaf extract against human bladder cancer T24 cells and investigated its phytochemical constituents through computational methods.
Saravana Prabha Poochi   +8 more
wiley   +1 more source

Treatment of Severe Refractory Hematuria due to Radiation-Induced Hemorrhagic Cystitis with Dexamethasone

open access: yesCase Reports in Medicine, 2017
Treatment of pelvic neoplasms with radiotherapy may develop sequelae, especially RHC. An 85-year-old male patient was admitted to a hospital emergency with gross hematuria leading to urinary retention and was diagnosed with RHC.
José Carlos Rodrigues Nascimento   +5 more
doaj   +1 more source

Sc(III) Complexes of Pyclen Derivative Ligands as Probes for Hypoxia: Synthesis, Chemical Characterization, 44Sc‐Radiolabeling, and Preclinical Assessment

open access: yesChemistry – A European Journal, EarlyView.
Hypoxia‐sensitive nitroimidazole‐functionalized pyclen derivatives were successfully synthesized and radiolabeled with 44Sc(III), affording stable and inert scandium complexes. Remarkable Sc(III)‐binding capabilities of the PC2A‐mono(amide) platform enabled excellent radiolabeling performance, with ≥92–99% yields and ≥99% radiochemical purity. MicroPET
Tibor Csupász   +9 more
wiley   +1 more source

Synthesis and Evaluation of Fluorinated Peptidomimetics Enabling the Development of 18F‐Labeled Radioligands Targeting Muscarinic Acetylcholine Receptor Subtype M3

open access: yesChemMedChem, EarlyView.
Fluorinated peptidomimetics targeting muscarinic acetylcholine receptor subtype M3: Fluorinated peptidomimetic compounds based on a β‐alanine‐glycine scaffold, with lead compound 24 demonstrating high M3 selectivity and submicromolar potency. The first M3‐selective positron emission tomography radioligand, [18F]24, is synthesized and will be evaluated ...
Miguel A. Herrera‐Rueda   +4 more
wiley   +1 more source

The impact of prior prostatic surgery on urinary continence in patients undergoing orthotopic ileal neobladder

open access: yesInternational Brazilian Journal of Urology, 2003
OBJECTIVE: To establish if previous surgery for benign prostatic hyperplasia (transurethral resection of the prostate or open prostatectomy), age, and preservation of prostatic apex can influence postoperative urinary continence in patients submitted to ...
Homero O. de Arruda   +4 more
doaj   +1 more source

Survivin and Her2 Expressions in Different Grades of Urothelial Neoplasms of Urinary Bladder [PDF]

open access: gold, 2021
Hedieh Moradi Tabriz   +4 more
openalex   +1 more source

Impacts of Diets and Food Plans in Health and Diseases—A Narrative Review

open access: yesFood Safety and Health, EarlyView.
This review emphasizes different diet types, providing insights into their nutritional content and health effects. Vegetarian and vegan diets, ketogenic diets, Mediterranean diets, Western diets, pescatarian diets, flexitarian diets, and territorial diversified diets are discussed, highlighting their influences on health, and diseases.
Md. Mahbubar Rahman   +3 more
wiley   +1 more source

Enfortumab vedotin plus pembrolizumab in treatment‐naïve metastatic urothelial carcinoma patients: An Austrian real‐world analysis

open access: yesInternational Journal of Cancer, EarlyView.
What's New? New antibody‐drug conjugates (ADCs) and immunotherapies have helped expand treatment options for urothelial carcinoma (UC). Clinical trials suggest that the ADC enfortumab vedotin (EV) and the immunotherapeutic agent pembrolizumab, when used in combination, are especially effective against UC.
Dora Niedersuess‐Beke   +30 more
wiley   +1 more source

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