Results 41 to 50 of about 34,171 (259)

Safety and pharmacokinetics of mosliciguat, a new, inhaled soluble guanylate cyclase activator, in healthy adult subjects

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mosliciguat (BAY 1237592), the first soluble guanylate cyclase (sGC) activator in a dry powder inhaler (DPI), could potentially treat pulmonary hypertension with a more targeted delivery than systemic sGC stimulators. We report safety and tolerability of mosliciguat in healthy men.
Johannes Nagelschmitz, Soundos Saleh, Sandra Ligges, Melanie Seidel‐Greven, Eva Becker‐Pelster, Sylvia M. Nikkho, Stefanie Boxnick, Wolfgang Timmer   +7 more
wiley   +1 more source

Validity of the International Prostate Symptoms Score in predicting urinary retention after joint replacement

Journal of Orthopaedic Surgery, 2019
Postoperative urinary retention necessitating catheterization after major lower limb arthroplasty surgery adds to the patients’ postoperative discomfort and increases the risk of urinary tract infection with potential risk of transient bacteraemia and ...
Alasdair JA Santini, Chetan A Jakaraddi, Fotis Polydoros, Sree Metikala   +3 more
doaj   +1 more source

MT‐RNR1 genotype testing for preventing aminoglycoside‐mediated ototoxicity: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, EarlyView.
Aminoglycosides are broad‐spectrum antibiotics used in the management of severe infections. Aminoglycosides are associated with nephrotoxicity and ototoxicity. Although dosing strategies such as once‐daily administration and therapeutic drug monitoring have reduced the incidence of nephrotoxicity, ototoxicity remains unpredictable and may occur at ...
John H. McDermott, Sian Hilton, Cinzia Dello Russo, Nicola Booth, Simon Drysdale, Philip Howard, Stephen Hughes, Mallinath Chakraborty, Helen McDevitt, Charlotte Alston, Maya Desai, Mike Beadsworth, Adam Reynolds, Serim Min, Katherine Payne, Munir Pirmohamed, William G. Newman   +16 more
wiley   +1 more source

Bladder drainage methods for acute urinary retention due to benign prostatic hyperplasia: patient-preference analysis

Вестник урологии
Introduction. Currently, the classical management of acute urinary retention creates a certain discomfort for the patient and leads to explore alternative method of management, such as intermittent catheterization, including focusing on the patient ...
A. I. Volnukhin, D. Yu. Pushkar, V. A. Malkhasyan   +2 more
doaj   +1 more source

Urinary catheterization and female genital mutilation [PDF]

Canadian Medical Association Journal, 2012
A 30-year-old African woman was admitted in labour at 37 weeks’ gestation of her fifth pregnancy for emergency cesarean delivery. This was her first assessment for the current pregnancy at this hospital. She had a cesarean delivery with each of her previous pregnancies.
openaire   +2 more sources

Same‐Day Discharge After Transcatheter Aortic Valve Implantation: Who, When, and How?

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT The burden of severe aortic stenosis requiring treatment is growing due to ageing populations. This places increased demands on health resources due to the growing number of transcatheter aortic valve implantation (TAVI) procedures and hospital bed occupancy.
Hilal Khan, Debbie Stewart, Sarah Lamb, Rajiv Das, Richard Edwards, Timothy Cartlidge, Mohammad Alkhalil, Azfar Zaman, Mohamed Farag   +8 more
wiley   +1 more source

Current Trends in the Management of Difficult Urinary Catheterizations

Western Journal of Emergency Medicine, 2012
Routine urinary catheter placement may cause trauma and poses a risk of infection. Male catheterization, in particular, can be difficult, especially in patients with enlarged prostate glands or other potentially obstructive conditions in the lower ...
Paul A Willette, Scott K Coffield
doaj  

Unusual complication of prolonged indwelling urinary catheter - iatrogenic hypospadias

Journal of Family Medicine and Primary Care, 2016
Long-time urethral catheterization may be responsible for various complications such as urethral stricture, urethral fracture, urinary tract infections, and hypospadias.
Gunjan Garg, Vishal Baghele, Naveen Chawla, Atul Gogia, Atul Kakar   +4 more
doaj   +1 more source

Association of Hospital Volume With Outcomes of Pulmonary Embolism in the United States

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Pulmonary embolism (PE) remains a leading cause of mortality in the United States. While prior studies show improved outcomes at higher‐volume centers, the understanding of procedural utilization remains limited. Aims Therefore, this study aimed to evaluate the association of hospital PE volume and intervention utilization with ...
Zihan Gao, Troy N. Coaston, Sidney Hinks, Nida Qadir, Obi Emeruwa, Peyman Benharash   +5 more
wiley   +1 more source

The Connected Catheter for management of Chronic Urinary Retention (CUR) in an adult male with Neurogenic Bladder – Case study

Urology Case Reports, 2019
Millions of adults suffer from chronic urinary retention or disorders that require catheterization for bladder management. The current standard of care for these patients consists of three different methods of catheterization, all of which present ...
Ernest Agatstein, Shahrad Aynehchi
doaj   +1 more source