Results 181 to 190 of about 34,363 (251)

Cost‐effectiveness of percutaneous nephrostomy vs JJ stent in obstructive urolithiasis: economic evaluation alongside the STent Or NEphrostomy (STONE) randomised controlled trial

open access: yesBJU International, EarlyView.
Objective To evaluate whether percutaneous nephrostomy (PCN) is cost‐effective compared to JJ ureteric stent in the acute treatment of obstructive urolithiasis. Patients and Methods A randomised controlled non‐inferiority trial with 204 patients with obstructive urolithiasis requiring decompression.
Hugo W. Schuil   +27 more
wiley   +1 more source

Targeted microwave ablation of localised prostate cancer (VIOLETTE trial): a prospective multicentre study

open access: yesBJU International, EarlyView.
Objective To assess the oncological outcomes of targeted microwave ablation (TMA) using organ‐based tracking (OBT) Fusion® via KOELIS Trinity® (KOELIS, Meylan, France) in men with intermediate‐risk prostate cancer (PCa): the VIOLETTE trial (ClinicalTrials.gov identifier: NCT04582656) Patients and Method In this prospective phase II, multicentre ...
Nicolas Barry Delongchamps   +11 more
wiley   +1 more source

Long‐term patient‐reported outcomes of open urorectal fistula repair after prostate cancer treatment

open access: yesBJU International, EarlyView.
Objectives To evaluate long‐term outcomes of open urorectal fistula (URF) repair, including URF recurrence, need for re‐intervention, and patient‐reported outcomes. Patients and Methods This retrospective study included men undergoing open URF repair between 2014 and 2024.
Max C. Wagner   +7 more
wiley   +1 more source

Patient‐reported outcome measures of percutaneous nephrostomy vs JJ stent in obstructive urolithiasis: results of the STent Or NEphrostomy (STONE) randomised controlled trial

open access: yesBJU International, EarlyView.
Objective To compare the effects of percutaneous nephrostomy (PCN) and JJ ureteric stent (JJ) for urinary tract decompression in patients with obstructive urolithiasis on health‐related quality of life (HRQoL), pain scores, urinary symptoms, and patient satisfaction.
Hugo W. Schuil   +25 more
wiley   +1 more source

Intravesical therapy for recurrent urinary tract infection: a systematic review and meta‐analysis

open access: yesBJU International, EarlyView.
Objective To undertake a systematic review and meta‐analysis to evaluate the efficacy, safety, and clinical applicability of intravesical instillations for preventing recurrent urinary tract infections (rUTIs). Methods PubMed/MEDLINE, Embase, Cochrane CENTRAL, Scopus, and Web of Science were searched from January 2000 to April 2025 for randomised and ...
Matthew Kwon   +3 more
wiley   +1 more source

Cytochrome P450 1A1 influences obesity‐induced pulmonary hypertension

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose The contribution of obesity to pulmonary arterial hypertension (PAH) pathophysiology remains poorly understood. Adipose tissue synthesises estrogens via cytochrome P450 (CYP) 19A1 (aromatase), whereas circulating estrogens are metabolised in the lung by CYP1A1.
Joshua P. Dignam   +12 more
wiley   +1 more source

Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions

open access: yesClinical Obesity, Volume 15, Issue 2, April 2025.
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton   +4 more
wiley   +1 more source

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