Results 71 to 80 of about 347,720 (286)

Fatores de risco e incidencia da infecção do trato urinario relacionada a cateterização vesical [PDF]

, 1994
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciencias da SaudeAnálise dos fatores de risco e incidência da infecção do trato urinário relacionada ao cateter vesical de demora, através de estudo observacional de coorte ...
Stamm, Ana Maria Nunes de Faria
core  

Evaluation of a pantoprazole and 4‐desmethylpantoprazole‐sulfate metabolic ratio as a novel CYP2C19 phenotyping method

British Journal of Clinical Pharmacology, EarlyView.
Aims CYP2C19 is one of the most important pharmacogenes, and its activity is highly variable due to factors such as genetics or drug–drug interactions. Due to the lack of an appropriate endogenous CYP2C19 biomarker, surrogate methods to assess its activity are warranted.
Julian Peter Müller, Vladimir N. Belov, Sabrina Yamoune, Bob Miller, Mohammed Hasoumi, Jolanta Tupiec, Thea Laurentius, L. Cornelius Bollheimer, Julia C. Stingl, Katja S. Just   +9 more
wiley   +1 more source

Safety and pharmacokinetics of mosliciguat, a new, inhaled soluble guanylate cyclase activator, in healthy adult subjects

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mosliciguat (BAY 1237592), the first soluble guanylate cyclase (sGC) activator in a dry powder inhaler (DPI), could potentially treat pulmonary hypertension with a more targeted delivery than systemic sGC stimulators. We report safety and tolerability of mosliciguat in healthy men.
Johannes Nagelschmitz, Soundos Saleh, Sandra Ligges, Melanie Seidel‐Greven, Eva Becker‐Pelster, Sylvia M. Nikkho, Stefanie Boxnick, Wolfgang Timmer   +7 more
wiley   +1 more source

Changing the culture: impact of a diagnostic stewardship intervention for urine culture testing and CAUTI prevention in an urban safety-net community hospital

Antimicrobial Stewardship & Healthcare Epidemiology
Cultures from urinary catheters are often ordered without indication, leading to possible misdiagnosis of catheter-associated urinary tract infections (CAUTI), increasing antimicrobial use, and C difficile.
Alfredo J. Mena Lora, Jessica Hua, Mirza Ali, Candice Krill, Eden Takhsh, Susan C. Bleasdale   +5 more
doaj   +1 more source

Ureteral Stents and Foley Catheters-Associated Urinary Tract Infections: The Role of Coatings and Materials in Infection Prevention

Antibiotics, 2014
Urinary tract infections affect many patients, especially those who are admitted to hospital and receive a bladder catheter for drainage. Catheter associated urinary tract infections are some of the most common hospital infections and cost the health ...
Joey Lo, Dirk Lange, Ben H. Chew
doaj   +1 more source

GRIA2 Variant Associated With Paradoxical Response to Perampanel Expanding the Spectrum of GRIA2‐Related Epileptic Encephalopathy: Case Report and Literature Review

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Introduction GRIA2 encodes the GluA2 ionotropic α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid (AMPA) receptor subunit. Pathogenic GRIA2 variants cause epilepsy, developmental delay, and neurobehavioral disorders. Characterizations of clinical features, including seizure types and their treatments, in patients with GRIA2‐related ...
Sai Srihitha Dommata, Chhitij Tiwari, Zheng Fan, Muge Gucsavas‐Calikoglu, Yael Shiloh‐Malawsky, Kimberly S. Foss, Stephanie N. Peck, Erin L. Heinzen, Chon Lee, Senyene E. Hunter   +9 more
wiley   +1 more source

Population Pharmacokinetics and Detection Times of Betamethasone After Intravenous, Intramuscular, and Intranasal Jet Administration of Betamethasone Sodium Phosphate in Horses

Drug Testing and Analysis, EarlyView.
Betamethasone concentrations in 20 horses from Japan and Germany following IV, IM, and INJ administration of betamethasone phosphate were analyzed using population pharmacokinetic modeling. For IV administration of 0.04 mg/kg q24 h, IPC and IUC were 0.012 and 0.31 ng/mL, respectively; the IUC approximated the IFHA urine ISL (0.20 ng/mL).
Taisuke Kuroda, Marc Machnik, Mario Thevis, Yohei Minamijima, Gary Ngai‐Wa Leung, Motoi Nomura, Fumiaki Mizobe, Yuhiro Ishikawa, Kazuhiro Kamiya, Pierre‐Louis Toutain   +9 more
wiley   +1 more source

Healthcare-associated urinary tract infection: epidemiology, burden of disease, and related factors at a teaching hospital in Ho Chi Minh City, Vietnam 2017–2022

Antimicrobial Stewardship & Healthcare Epidemiology
Introduction: Urinary tract infection (UTI) is a common healthcare-associated problem. UTI has a lower mortality prevalence than other infections, but it is at high risk of leading to sepsis and increased treatment costs.
Huynh Minh Tuan, Pham Thi Truong Ngan, Nguyen Vu Hoang Yen, Trinh Thi Thoa, Truong Thi Le Huyen, Huynh Hoang Hai, Le Thanh Truyen, Nguyen Thi Minh Khai, Le Thi Yen Nhi, Pham Thi Lan   +9 more
doaj   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Urinary pH and the Indwelling Catheter

Upsala Journal of Medical Sciences, 1980
The pH of the urine within a blocked indwelling catheter was significantly higher than the pH of the first urine portion from the new catheter. This observation suggests that the urinary pH was changed in an alkaline direction within the indwelling catheter, probably due to the production of ammonia induced by urease from Proteus strains.
A, Norberg, B, Norberg, K, Lundbeck, U, Parkhede   +3 more
openaire   +2 more sources