Results 31 to 40 of about 10,481 (197)
The Journal of Clinical Pharmacology, EarlyView.Abstract Fezolinetant is a non‐hormonal, selective neurokinin 3 receptor antagonist approved in multiple countries including the United States, in Europe, and in Asia for the treatment of moderate to severe vasomotor symptoms in menopausal women. Fezolinetant is primarily metabolized by CYP1A2 and was found to be a sensitive substrate for CYP1A2 ...
Mary P. Choules +4 more
wiley +1 more source
Electrokinetic Manipulations Combined With Direct and Ambient Ionization Mass Spectrometry
Mass Spectrometry Reviews, EarlyView.ABSTRACT Mass spectrometry (MS) is a powerful analytical technique that typically involves sample preparation and online analytical separation before MS detection. Traditional methods often face bottlenecks in sample preparation and analytical separation, despite the rapid detection capabilities of MS.
Nicholas E. Manicke +2 more
wiley +1 more source
Neurourology and Urodynamics, EarlyView.ABSTRACT Objective This study aimed to analyze the outcomes of clinical management of patients with interstitial cystitis (IC). Patients and Methods We retrospectively analyzed the electronic medical records of patients with IC who visited outpatient clinics with pelvic pain between October 2005 and December 2019.
Hyun Ju Jeong +4 more
wiley +1 more source
Oikos, EarlyView.Human‐induced climate change is a driver of extinction, with extreme events occurring more frequently. It increases both the amount and fluctuations in environmental stress that organisms experience. In such environments, greater intra‐specific trait variation creates more potential for adaptation through natural selection.
Meng‐Han Joseph Chung +2 more
wiley +1 more source
People and Nature, EarlyView.Abstract Human‐wildlife conflicts (HWCs) are one of the most critical conservation challenges worldwide. Large carnivores are frequently at the centre of these conflicts because of the perceived and real threats they pose to livestock and human safety.
Esperanza C. Iranzo +10 more
wiley +1 more source
Three and Four Courses of Radiation for Children with Recurrent Diffuse Intrinsic Pontine Glioma
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose Re‐irradiation (RT2) for children with diffuse intrinsic pontine glioma (DIPG) is increasingly used upon recurrence; however, limited data are available for evaluating additional courses of radiotherapy (RT) for DIPG. The purpose of this case series was to report our institutional experience in treating patients with recurrent DIPG ...
Nisha Shariff +3 more
wiley +1 more source
Prenatal Diagnosis, EarlyView.ABSTRACT Aim The role of prenatal urinoma in lower urinary tract obstruction (LUTO) such as posterior urethral valves (PUV) is debated. We aimed to describe the risk factors associated with fetal urinoma and the association between fetal urinoma and postnatal renal function before 2 years of age.
Flore‐Anne Martin +10 more
wiley +1 more source
PM&R, EarlyView.Abstract Background Popular programs to combat the increased rates of falls and improve overall balance and strength in the aging population are limited by accessibility or focus on distal movements, thereby limiting gains from the programs. The use of an age‐appropriate, community‐based Pilates program focusing on core strengthening for improved ...
Luigi Gonzales +4 more
wiley +1 more source
United European Gastroenterology Journal, EarlyView.ABSTRACT Malabsorption is a complex and multifaceted condition characterised by the defective passage of nutrients into the blood and lymphatic streams. Several congenital or acquired disorders may cause either selective or global malabsorption in both children and adults, such as cystic fibrosis, exocrine pancreatic insufficiency (EPI), coeliac ...
Marco Vincenzo Lenti +29 more
wiley +1 more source
Dissecting Microscopic Colitis Immunopathophysiology: Insights From Basic Research
United European Gastroenterology Journal, EarlyView.ABSTRACT Microscopic colitis is an inflammatory bowel disease (IBD) comprising two clinically undiscernible entities: collagenous colitis and lymphocytic colitis. Collagenous colitis associates with HLA genes and displays a Th1/Tc1–Th17/Tc17 profile with pericryptal myofibroblast activity, water malabsorption and secondary fluid loss due to altered ...
Andreas Münch +1 more
wiley +1 more source