Results 81 to 90 of about 671,874 (331)

Evaluation of Therapeutic Opioids in Hair of Neonatal and Pediatric Patients

Drug Testing and Analysis, EarlyView.
This study investigated the incorporation of novel and traditional medically used opioids into the hair of 118 pediatric and neonatal patients. Concentrations (median [range]) in hair were as follows: fentanyl: 4.03 pg/mg [0.10–343], sufentanil: 0.31 pg/mg [0.10–8.64], remifentanil: 0.14 pg/mg [0.10–0.43], and morphine: 27.4 pg/mg [1.0–1870].
Max Polke, Florian Zapf, Tanja Restin, Thomas Kraemer, Tina M. Binz   +4 more
wiley   +1 more source

Origin and Interpretation of Low Methamphetamine Levels Found in Amphetamine‐Positive Urine Samples: Support for Methylation of Amphetamine as a Minor Metabolic Pathway

Drug Testing and Analysis, EarlyView.
A low urinary concentration of methamphetamine less than 1% of the amphetamine level may not necessarily indicate polydrug use. Instead, it could result from N‐methylation of amphetamine. Chiral analysis of both amphetamines is an effective method for distinguishing between illicit use and therapeutic sources in positive drug screening results ...
Anders Helander, Annika Andersson, Tomas Villén   +2 more
wiley   +1 more source

Integrating host condition into spatiotemporal multiscale models improves virus shedding predictions

Ecography, EarlyView.
Understanding where and when pathogens occur in the environment has implications for reservoir population health and infection risk. In reservoir hosts, infection status and pathogen shedding are affected by processes interacting across different scales: from landscape features affecting host location and transmission to within‐host processes affecting
Andrew M. Kramer, Christina L. Faust, Adrian A. Castellanos, Ilya R. Fischhoff, Alison J. Peel, Peggy Eby, Manuel Ruiz‐Aravena, Benny Borremans, Raina K. Plowright, Barbara A. Han   +9 more
wiley   +1 more source

Adjuvant pharmacological strategies for the musculoskeletal system during long‐term space missions

British Journal of Clinical Pharmacology, EarlyView., 2023
Abstract Despite 2 h of daily exercise training, muscle wasting and bone loss are still present after 6‐month missions to the international space station. Some crew members lose bone much faster than others. In preparation for missions to the Moon and Mars, space agencies are therefore reviewing their countermeasure portfolios.
Friederike Thomasius, Dominik Pesta, Jörn Rittweger   +2 more
wiley   +1 more source

The Use of Regenerative Medicine in the Management of Invasive Bladder Cancer

Advances in Urology, 2012
Muscle invasive and recurrent nonmuscle invasive bladder cancers have been traditionally treated with a radical cystectomy and urinary diversion. The urinary diversion is generally accomplished through the creation of an incontinent ileal conduit ...
Matthew E. Hyndman, Deborah Kaye, Nicholas C. Field, Keith A. Lawson, Norm D. Smith, Gary D. Steinberg, Mark P. Schoenberg, Trinity J. Bivalacqua   +7 more
doaj   +1 more source

Cancer of the vagina: 2025 update

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Primary vaginal cancer is a rare gynecologic malignancy, with most vaginal cancers representing metastases from other primary sites. Staging and treatment protocols are often extrapolated from those used in cervical cancer. In contemporary medicine, the roles of the pathologist and radiologist are increasingly vital in supporting diagnosis and
Tracey S. Adams, Jackie Choekoe Maluleke, Mauricio A. Cuello   +2 more
wiley   +1 more source

Bricker Technique of Uretero‐Ileal Anastomosis for Duplex Ureters Undergoing Intracorporeal Ileal Conduit Construction

IJU Case Reports, EarlyView.
ABSTRACT Introduction Bladder cancer in patients with ureteral anomalies presents unique surgical challenges, particularly regarding urinary diversion. This case highlights a novel approach to uretero‐ileal anastomosis in a patient with duplicated right ureters undergoing radical cystectomy.
Kyotaro Fukuta, Ryoichi Nakanishi, Keito Shiozaki, Seiya Utsunomiya, Yutaro Sasaki, Takeshi Nakashima, Tomoya Fukawa, Hirofumi Izaki, Junya Furukawa   +8 more
wiley   +1 more source

Comparative Analysis of Percutaneous Nephrostomy and Double J Stenting in Upper Urinary Tract Obstruction with Acute Kidney Injury: A Tertiary Hospital Based Prospective Study

National Board of Examinations Journal of Medical Sciences
Background: Upper urinary tract obstruction is a serious condition that can lead to significant renal impairment if not managed promptly. Emergency urinary diversion is crucial for alleviating obstruction and preserving renal function.
Manzoor Ahmad, Vivek Pachauri, Saif Quaiser, Wasif Md Ali, Imad Ali, Adnan Habib   +5 more
doaj   +1 more source

Synchronous enteroid adenocarcinoma at the ureteral implantation site after ureterosigmoidostomy

Urology Case Reports, 2022
Ureterosigmoidostomy is considered to be the oldest urinary diversion technique performed for the first time in the 19th Century in patients with urinary malformations. However, the high rate of complications as well as the significant risk of developing
B. Gómez González, A. Hevia Feliú, D. Serralta de Colsa, S. Salinas Moreno, I. González-Valcarcel de Torres, J.M. De la Morena Gallego   +5 more
doaj  

Successful Management of Tumor Lysis Syndrome Following Enfortumab Vedotin Plus Pembrolizumab Therapy in Metastatic Urothelial Carcinoma: A Case Report

IJU Case Reports, EarlyView.
ABSTRACT Introduction Enfortumab vedotin plus pembrolizumab (EV + P) shows high efficacy in metastatic urothelial carcinoma (mUC), potentially increasing tumor lysis syndrome (TLS) risk. Case Presentation A 64‐year‐old man with mUC underwent surgery and adjuvant nivolumab after neoadjuvant chemotherapy.
Daigo Takemori, Ryu Shigehisa, Sho Shimasaki, Erika Yamashita, Yoshitaka Kurano, Kaya Atagi, Yuhi Ota, Shinkuro Yamamoto, Hiroto Osakabe, Tomoya Nao, Tsutomu Shimamoto, Hideo Fukuhara, Nobutaka Shimizu, Satoshi Fukata, Shingo Ashida, Keiji Inoue   +15 more
wiley   +1 more source