Results 241 to 250 of about 911,968 (335)

Diagnostic and Therapeutic Roles of Extracellular Vesicles in Chronic Kidney Disease: A Systematic Review

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.
This systematic review compiles and analyses 364 studies on chronic kidney disease (CKD) that investigated extracellular vesicles (EVs) for diagnostic and therapeutic applications. By systematically categorizing data according to EV source and cargo, it provides an integrated overview of EV application for CKD, highlighting common approaches and shared
Tunahan Ergunay   +2 more
wiley   +1 more source

Antenatal Presentation of MRPS22‐Related Mitochondrial Disease Confirmed With Rapid Proteomics

open access: yesJIMD Reports, Volume 67, Issue 3, May 2026.
ABSTRACT MRPS22‐related mitochondrial disease (MIM#611719) is a rare autosomal recessive disorder caused by defects in the mitochondrial ribosomal protein S22, a component of the small mitoribosomal subunit essential for mitochondrial translation. Of the few reported cases, most present antenatally with a severe phenotype, conveying a poor prognosis ...
Liana N. Semcesen   +43 more
wiley   +1 more source

Primary hypospadias in adults : tips and tricks [PDF]

open access: yes, 2016
Hoebeke, Piet, Spinoit, Anne-Françoise
core  

XIAP Deficiency Impairs Colonic Tuft Cell Development and Predisposes to Crohn's Disease

open access: yesMedComm, Volume 7, Issue 5, May 2026.
XIAP deficiency leads to impaired colonic tuft cells development and JAK–‐STAT pathway hyperactivation in CD patients and mice. Mechanically, XIAP regulates tuft cells development through Wnt–‐TLE4/TCF–‐ASCL2 signaling. Tuft cells deficiency predisposes XIAP‑‐deficient CD patients or Xiap−/−‐/‐ mice to hazardous microbial effects, driving colonic ...
Rongli Fang   +28 more
wiley   +1 more source

Comparison of Signal‐ and Volume‐Based Ventilation‐Weighted Assessment Using 3D FLORET UTE MRI in Patients With Various Pulmonary Disease

open access: yesMagnetic Resonance in Medicine, Volume 95, Issue 5, Page 2814-2827, May 2026.
ABSTRACT Purpose 3D free‐breathing, proton, contrast‐agent‐free MR methods are increasingly used for pulmonary ventilation‐weighted measurements. The methods are split between: (1) signal‐based, which rely on lung parenchyma signal changes during respiration, and (2) volume‐based that utilize the Jacobian determinant of deformation fields from the ...
Filip Klimeš   +12 more
wiley   +1 more source

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