Results 81 to 90 of about 802,359 (381)

Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Food Effect of Bexicaserin in Healthy Participants: A First‐in‐Human Randomized, Double‐Blind, Placebo‐Controlled Single Ascending Dose Escalation Phase 1 Study

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Bexicaserin (LP352) is a selective 5‐hydroxytryptamine 2C (5‐HT2C) superagonist in development for the treatment of seizures in developmental and epileptic encephalopathies (DEEs). This double‐blind, placebo‐controlled, single ascending dose (SAD) Phase 1 study aimed to assess the safety, tolerability, and pharmacokinetic (PK) and ...
Rosa Chan   +6 more
wiley   +1 more source

Tackling Ageing Continence through Theory, Tools & Technology [PDF]

open access: yes, 2012
Originally presented at ‘Aging and Society: An Interdisciplinary Conference’, University of California, Berkeley (2011), this article was double-blind peer reviewed, receiving scores of 96% and 73%. It outlines the interdisciplinary research of the cross-
Bichard, Jo-Anne   +8 more
core   +3 more sources

Prevalence and sociodemographic correlates of urinary incontinence in Japanese women: A web-based cross-sectional study

open access: yesWomen's Health, 2023
Background: Epidemiological studies on urinary incontinence that used a validated international standard questionnaire are limited in Japan, and few studies have examined the sociodemographic and behavioral correlates of urinary incontinence.
Aki Onishi, Ai Shibata
doaj   +1 more source

Overweight and obesity as major, modifiable risk factors for urinary incontinence in young to mid‐aged women: a systematic review and meta‐analysis

open access: yesObesity Reviews, 2018
The purpose of this review and meta‐analysis was to evaluate overweight and obesity as risk factors for urinary incontinence in young to mid‐aged women.
T. Lamerton, L. Torquati, Wendy J. Brown
semanticscholar   +1 more source

Neuromodulation in neurogenic bladder. [PDF]

open access: yes, 2016
While neuromodulation is a well-established treatment option for patients with non-neurogenic overactive bladder and urinary retention, its applicability to the neurogenic bladder population has only recently been examined more in depth.
Sanford, Melissa T, Suskind, Anne M
core   +1 more source

Self‐completed patient‐reported outcome measures in adults with epilepsy: A review

open access: yesEpilepsia Open, EarlyView.
Abstract Epilepsy affects 65 million people worldwide, and is a World Health Organization priority disease as highlighted in their 2022–2031 Intersectoral Global Action Plan (IGAP) on Epilepsy and other Neurological Disorders. IGAP's objectives include improving epilepsy treatment and care.
Alison L. Conquest   +5 more
wiley   +1 more source

Variation in availability and use of surgical care for female urinary incontinence: a mixed-methods study

open access: yesHealth Services and Delivery Research, 2021
Background: Urinary incontinence affects between 25% and 45% of women. The availability and quality of services is variable and inequitable, but our understanding of the drivers is incomplete. Objectives: The objectives of the study were to model patient,
Rebecca S Geary   +8 more
doaj   +1 more source

Impacts of Diets and Food Plans in Health and Diseases—A Narrative Review

open access: yesFood Safety and Health, EarlyView.
This review emphasizes different diet types, providing insights into their nutritional content and health effects. Vegetarian and vegan diets, ketogenic diets, Mediterranean diets, Western diets, pescatarian diets, flexitarian diets, and territorial diversified diets are discussed, highlighting their influences on health, and diseases.
Md. Mahbubar Rahman   +3 more
wiley   +1 more source

Mobile app for treatment of stress urinary incontinence: A randomized controlled trial

open access: yesNeurourology and Urodynamics, 2017
To evaluate the effect of a mobile app treatment for stress urinary incontinence (SUI) in women.
I. Asklund   +5 more
semanticscholar   +1 more source

Effectiveness and cost-effectiveness of basic versus biofeedback-mediated intensive pelvic floor muscle training for female stress or mixed urinary incontinence: protocol for the OPAL randomised trial [PDF]

open access: yes, 2019
This is the final version. Available on open access from BMJ Publishing Group via the DOI in this recordIntroduction Accidental urine leakage is a distressing problem that affects around one in three women. The main types of urinary incontinence (UI) are
Abdel-Fattah, Mohamed   +18 more
core   +5 more sources

Home - About - Disclaimer - Privacy