Results 101 to 110 of about 13,172 (188)
Medium to severe iodine deficiency still exists in Abkhazia
Background.Due to historical reasons, Abkhazia is one of the few regions of the formerSoviet Unionwhere status of iodine nutrition of the population is still unknown and activities for the prevention of iodine deficiency are not carried out.
Gregory A. Gerasimov +4 more
doaj +1 more source
An endemic Aurès chemotype of Salvia balansae emerges as a rich source of luteolin, rosmarinic acid, and other polyphenols with potent antioxidant and NLRP3‐linked anti‐inflammatory activities. Protection against experimental inflammation, favorable enzyme‐modulating properties, and a wide safety margin highlight its promise as a pharmaceutical and ...
Khadra Afaf Bendrihem +16 more
wiley +1 more source
This study establishes [68Ga]Ga‐DOTA‐AP9 as a first‐in‐human CD147‐targeted PET tracer with favorable safety and specific tumor uptake. Tracer accumulation correlates with CD147 expression in patients, enabling noninvasive quantification of CD147‐positive malignancies.
Xiaokun Ma +10 more
wiley +1 more source
Radioiodine‐refractory differentiated thyroid cancer (RAIR‐DTC) management now spans selective kinase inhibitors, MAPK‐pathway redifferentiation, VEGFR multikinase TKIs, and biomarker‐driven immunotherapy. We propose a three‐axis decision framework integrating molecular driver, evidence level, and patient dimension to guide individualized treatment ...
Yamin Li, Zuoxiang He
wiley +1 more source
Excreção urinária de iodo em lactentes segundo as características pós parto
To evaluate the concentration of iodine in the urine of infants (ioduria) and its possible relation to the postpartum characteristics of the newborn infant, and to assess the concentration of iodine in table salt, since this is the food with the ...
Livia Fernandes de LIMA +1 more
doaj
Arterial Perivascular Space‐Mediated Solute Transport in the Mouse Brain
The mechanisms underlying solute clearance from the brain parenchyma remain debated, with competing hypotheses involving bulk cerebrospinal fluid flow versus perivascular transport. Using multimodal in vivo imaging and computational modeling in mice, this study demonstrates that arterial pulsation drives bidirectional solute movement within the ...
Shiyong Li +9 more
wiley +1 more source
Environmental toxicants may disrupt developmental pathways via strong molecular docking interactions with hub FGF proteins (FGF9 and FGF4) like dibenzo‐p‐dioxin (−7.2 kcal/mol) at the ASN146 residue of FGF9, driving congenital malformations as revealed by PPI networks and toxicity profiling.
Adarsh Kumar Shukla +3 more
wiley +1 more source
Phenolic composition and multi‐target bioactivities of Globularia alypum extracts across seasons
Abstract Background This study investigates the influence of seasonal variation on the phytochemical profile and biofunctional activities of ethanolic leaf extracts from Globularia alypum. Leaves collected across four seasons were extracted with a hydroethanolic solvent (80:20, v/v) and analyzed by LC‐ESI‐MS/MS.
Mohammed Messaoudi +11 more
wiley +1 more source
BackgroundDespite the universal iodization of salt in Ethiopia, iodine deficiency disorder remains a major public health problem and continued to affect a large segment of the population.
Hamid Yimam Hassen +2 more
doaj +1 more source
Abstract Autism spectrum disorder (ASD) in children is a major public health challenge. The potential epidemiological links between heavy metal exposure and ASD remains a controversial issue. This critical review examines the epidemiological discrepancies, including variations in exposure assessment, study design, and population differences that ...
Aporajita Das Trisha +3 more
wiley +1 more source

