Results 161 to 170 of about 175,640 (264)

Aberrant glycosylation of IgG in children with active lupus nephritis alters podocyte metabolism and causes podocyte injury

open access: yesArthritis &Rheumatology, Accepted Article.
Background Podocytes are integral to the maintenance of the glomerular filtration barrier. Their injury results in proteinuria and disease progression in lupus nephritis (LN). Aberrant IgG glycosylation drives podocyte injury in LN and leads to cytoskeletal rearrangement, motility changes and decreased nephrin production.
Rhea Bhargava   +9 more
wiley   +1 more source

The history of anatomical engagement

open access: yesAnatomical Sciences Education, EarlyView.
Abstract The public's fascination with anatomy has evolved over time and progressed from avoidance of the tainted yet saintly corpse, to their fascination with cabinets of curiosities. The current narrative review explores public engagement (PE), from its potential origins as cave paintings, to the rise of the disciplinarity of anatomy.
Quenton Wessels, Adam M. Taylor
wiley   +1 more source

A limited global perspective on what makes anatomical public engagement good or bad

open access: yesAnatomical Sciences Education, EarlyView.
Abstract Anatomical public engagement has the potential to enhance anatomical literacy and patient–provider communication. However, the lack of consensus on effective practices, ethical considerations, and cultural sensitivities poses challenges for anatomists conducting outreach events.
Victoria Gomez   +3 more
wiley   +1 more source

Identifying Daily Living Skills From Childhood and Adolescence Predictive of Adult Outcomes in a Longitudinal Study of Autism and Related Developmental Conditions

open access: yesAutism Research, EarlyView.
ABSTRACT Challenges in daily living skills (DLS) are well‐documented in autism and other developmental conditions. Research has also cataloged challenges in adult outcome attainment among autistic individuals and those with other developmental conditions; stronger DLS are associated with a higher likelihood of attaining some adult outcomes. Little work
Elaine B. Clarke, Catherine Lord
wiley   +1 more source

First‐in‐human safety, tolerability, pharmacokinetics and pilot food‐effect study of the candidate antimalarial compound MMV367

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim To evaluate the safety, tolerability and pharmacokinetics in healthy participants of orally administered MMV367 (GSK3772701), a novel antimalarial interfering with Plasmodium falciparum acyl coenzyme A synthetase 10/11 function. Methods This first‐in‐human study enrolled 47 healthy male and female participants.
Andrea Kuemmerle   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy