Results 161 to 170 of about 866,426 (291)
NIBV Induces Incomplete Autophagy via AMPK‐TFEB, Causing Kidney Injury in Chicks
Advanced Science, EarlyView.This study reveals that NIBV can inhibit the nuclear translocation of TFEB by suppressing the expression of AMPK, leading to the blockade of autophagolysosomal functions, in turn increasing NIBV replication and triggering severe kidney injury in chicks.
Cheng Huang +10 more
wiley +1 more source
Correlations between maternal illnesses and congenital malformations of the kidney and urinary system in offspring: A cohort study. [PDF]
Medicine (Baltimore)Bu W, Li X, Yan X, Hu X, Zhao Z.
europepmc +1 more source
Actomyosin Activity and Piezo1 Activity Synergistically Drive Urinary System Fibroblast Activation. [PDF]
Adv Sci (Weinh), 2023 Chen G +8 more
europepmc +1 more source
Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy
Advanced Science, EarlyView.Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong +5 more
wiley +1 more source
The role and mechanism of human papillomavirus in urinary system tumors. [PDF]
J Int Med ResHuang H, Feng S, Liu Y.
europepmc +1 more source
Advanced Science, EarlyView.This study generates high‐fidelity synthetic longitudinal records for a million‐patient diabetes cohort, successfully replicating clinical predictive performance. However, deeper analysis reveals algorithmic biases and trajectory inconsistencies that escape standard quality metrics. These findings challenge current validation norms, demonstrating why a
Francisco Ortuño +5 more
wiley +1 more source
The role of m5C, m1A and m7G modifications in tumors of urinary system. [PDF]
Front Cell Dev BiolXue W +5 more
europepmc +1 more source