Results 211 to 220 of about 1,744,557 (311)

Diagnostic value of flow cytometric urine analysis in urinary tract infections of newborns and infants. [PDF]

Sci Rep
Gülcan Kersin S, Yanılmaz Ö, İlki ZA, Bilgen HS.   +3 more
europepmc   +1 more source

A multipart phase 1 study of the safety, pharmacodynamics and pharmacokinetics of ALG‐055009, a novel thyroid hormone receptor beta (THR‐β) agonist for metabolic dysfunction‐associated steatohepatitis (MASH), in healthy participants

Clinical Pharmacology in Drug Development, EarlyView.
Abstract ALG–055009 is an oral thyroid hormone receptor beta (THR‐β) agonist being evaluated for treating metabolic dysfunction–associated steatohepatitis (MASH). This study evaluated the safety, tolerability, pharmacokinetics, and pharmacodynamics of ALG‐055009 and bioavailability/food effect.
Hakim Charfi, Benedetta Massetto, Megan Fitzgerald, Kha Le, Stanley Wang, Ifong Kan‐Eng, Meenakshi Venkatraman, Naqvi Mohammad, Lawrence Blatt, Tse‐I Lin, Sushmita M. Chanda, John Fry   +11 more
wiley   +1 more source

Multidisciplinary meetings for lower urinary tract symptoms and benign prostate hyperplasia. [PDF]

BJUI Compass
Seizilles de Mazancourt E, Abid N, Pagnoux G, Rouvière O, Codas Duarte R, Ruffion A, Fassi Fehri H.   +6 more
europepmc   +1 more source

Antibiotic resistance in pathogens causing community-acquired urinary tract infections in India: a multicenter study

, 2008
Atul Kothari, Vishal Sagar
openalex   +2 more sources

Bacteriophages of the lower urinary tract

Nature reviews. Urology, 2019
Andrea Garretto, Taylor Miller-Ensminger, A. Wolfe, C. Putonti   +3 more
semanticscholar   +1 more source

Assessment of Pharmacokinetic Drug Interaction of Asciminib with Atorvastatin in Healthy Participants

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Asciminib is the first BCR::ABL1 inhibitor that Specifically Targets the ABL Myristoyl Pocket (STAMP) in patients with chronic myeloid leukemia. This phase 1, two‐treatment‐period, drug‐drug interaction study evaluated the effect of steady‐state asciminib on the pharmacokinetics of atorvastatin.
Matthias Hoch, Wendy Weis, Felix Huth, Seshulatha Jamalapuram, Michelle Quinlan, Amarnath Bandaru, Suleyman Eralp Bellibas, Asmae Mirkou, Shruti Kapoor, Shefali Kakar   +9 more
wiley   +1 more source

Effects of High‐ and Low‐Fat Meals on the Bioavailability and Pharmacokinetics of Votoplam, a HTT Gene Splicing Modifier

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Votoplam is a novel, orally bioavailable, small molecule HTT gene splicing modifier that is being developed for the treatment of Huntington's disease. This was a single dose, open‐label, two‐period, crossover food effect study that evaluated the effect of high‐ and low‐fat meals on 20 mg votoplam in healthy participants. There was a washout of
Lucy Lee, Amy‐Lee Richards, Nageswara Reddy, Brian Beers, Lee Golden, Ronald Kong   +5 more
wiley   +1 more source

Zoonotic <i>Escherichia coli</i> and urinary tract infections in Southern California. [PDF]

mBio
Aziz M, Park DE, Quinlivan V, Dimopoulos EA, Wang Y, Sung EH, Roberts ALS, Nyaboe A, Davis MF, Casey JA, Caballero JD, Nachman KE, Takhar HS, Aanensen DM, Parkhill J, Tartof SY, Liu CM, Price LB, KP & GWU ARES team.   +18 more
europepmc   +1 more source

Innate immunity and urinary tract infection

Pediatric nephrology (Berlin, West), 2019
C. Ching, L. Schwartz, J. Spencer, B. Becknell   +3 more
semanticscholar   +1 more source

Innovative Drugs Approved in China After Registration Classification Reform: Current Status, Disparities, and Challenges

Clinical Pharmacology &Therapeutics, EarlyView.
Since 2016, the China National Medical Products Administration (NMPA) has reformed its drug registration classification rules and defines the innovative drugs as new drugs that have not been marketed domestically and overseas. This study sought to systematically evaluate the characteristics of the innovative drugs approved in China. The cross‐sectional
Xingyue Zhu, Die Xiao
wiley   +1 more source