Results 191 to 200 of about 2,387,502 (293)

Tofacitinib Regulates β‐Catenin Nuclear Translocation to Inhibit FLS Migration and Alleviate Clinical Symptoms of RA

iNew Medicine, EarlyView.
ABSTRACT Objective Tofacitinib is a Janus kinase (JAK) inhibitor approved for the treatment of moderate‐to‐severe rheumatoid arthritis (RA). However, its synovium‐related molecular mechanisms, particularly its regulatory effect on fibroblast‐like synoviocyte (FLS) migration, remain incompletely understood.
Shuqi Fang, Tianjing Zhang, Ling Hu, Ruijin Liu, Leyi Jia, Menglin Bai, Jiale Dong, Yuchen Zhao, Han Wang, Lei Zhang, Tao Li, Youcai Deng, Xianzheng Zhang, Lingling Zhang   +13 more
wiley   +1 more source

Aerococcus mictus as a cause of feline urinary tract infection: a case report. [PDF]

BMC Vet Res
Uva A, Pirolo M, Cavalera MA, Tanas G, Guardabassi L, Zatelli A, Gernone F.   +6 more
europepmc   +1 more source

Epigenetically Regulated NOX4/NRF2 Axis Mediates PM2.5‐Induced Ferroptosis and Inflammatory Response in Membranous Nephropathy

Journal of Applied Toxicology, EarlyView.
ABSTRACT This study aims to explore the involvement and mechanism of ferroptosis in particulate matter 2.5 (PM2.5)–induced membranous nephropathy (MN) progression. A cationic bovine serum albumin (cBSA)–induced mouse model of MN was established, followed by PM2.5 exposure.
Yanhong Gao, Yinfeng Guo, Shaoyan Xu, Min Zhang, Yanxia Rui, Shujun Pan, Changhua Zhou, Jianxiang Chen, Henglan Wu   +8 more
wiley   +1 more source

Pharmacists' Management of Urinary Tract Infection Symptoms in Community Pharmacy: Counseling Practices and Attitudes Toward Antibiotic Therapy. [PDF]

Pharmacy (Basel)
Jovanović A, Veličković Radovanović R, Tadić I, Drobac M, Vidović B, Pavlović D, Odalović M, Krajnović D.   +7 more
europepmc   +1 more source

Organ‐Specific Human Microbiomes and Dysbiosis: Mechanistic Links to Disease and Emerging Therapeutic Strategies

Journal of Clinical Laboratory Analysis, EarlyView.
Schematic overview of the human microbiome and major microbiota‐derived metabolites across body sites, highlighting the gut–brain, gut–heart, and gut–kidney axes in host physiology and disease. ABSTRACT Background The human microbiome is a dynamic and diverse community of microorganisms that affects susceptibility to illness and promotes wellness ...
Awadh Alanazi
wiley   +1 more source

Combined phage therapy and faecal microbiota transplantation to treat recurrent urinary tract infection: a case series. [PDF]

Nat Microbiol
McCallin S, Classen AY, Lieberknecht-Jouy SC, Abdula F, Dugas S, Gross O, Koliwer-Brandl H, Lassen S, Scheidegger J, Dunne M, Kahles A, Eigler J, Farowski F, Higgins PG, Milek S, Chemych O, Du J, Loessner MJ, Kessler TM, Vehreschild MJGT, Leitner L, Biehl LM.   +21 more
europepmc   +1 more source

Clinical and Cytogenomic Characterization of Three Patients With Distal 1q43q44 Deletion: Twin Sisters With a de novo Deletion and a Patient With der(1)t(1;21)(q43;q22.3)mat

Journal of Clinical Laboratory Analysis, EarlyView.
Distal 1q43q44 deletions lead to a consistent neurodevelopmental phenotype characterized by microcephaly, corpus callosum abnormalities, and developmental delay. Despite differences in genomic architecture, overlapping deletions affecting dosage‐sensitive genes such as AKT3, HNRNPU, and ZBTB18 define the core phenotype.
Ma. Guadalupe Domínguez‐Quezada, Horacio Rivera, Luis E. Figuera, Patricio Barros‐Núñez, José Luis Castrillo, Carlos Córdova‐Fletes, Thania Alejandra Aguayo‐Orozco   +6 more
wiley   +1 more source

Oral antibiotic exposure and urinary tract infection risk in adults: a self-controlled case series study. [PDF]

EClinicalMedicine
Deelen M, van Dijk WJ, Boelens M, Borgdorff H, Lambregts MM, van Nieuwkoop C, Sijbom M.   +6 more
europepmc   +1 more source

Diagnosis by Resolution: Ultrasound Follow‐Up of Neonatal Polypoid Cystitis Mimicking Botryoid Rhabdomyosarcoma

Journal of Clinical Ultrasound, EarlyView.
In neonatal bladder masses, benign inflammatory conditions like polypoid cystitis can mimic malignancy on ultrasound. In stable neonates with evidence of infection, short‐interval ultrasound follow‐up after antibiotic therapy allows “diagnosis by resolution.” This conservative approach safely avoids unnecessary invasive procedures while maintaining ...
Davide Meneghesso, Mattia Pasquinucci, Martina Bruniera, Filippo Carletti, Alessandro Morlacco   +4 more
wiley   +1 more source

Does Preoperative Mixed-Growth Urine Culture Increase the Risk of Urinary Tract Infection After Ureteroscopic Stone Treatment? A Retrospective Study. [PDF]

Health Sci Rep
Mahmoud KE, Al-Qudimat AR, Alhusban AK, Al-Zoubi RM, Elaarag M, Alobiedly A, Khalil IA, AlAnsari A.   +7 more
europepmc   +1 more source