Results 141 to 150 of about 381,673 (307)

Urinary Tract Infection [PDF]

open access: green, 1961
Denis O’Sullivan   +3 more
openalex   +1 more source

Urinary tract infections: epidemiology, mechanisms of infection and treatment options

open access: yesNature Reviews Microbiology, 2015
A. Flores-Mireles   +3 more
semanticscholar   +1 more source

Efficacy, Safety, Pharmacokinetics, and Immunogenicity of ABBV‐154 in Adults With Glucocorticoid‐Dependent Polymyalgia Rheumatica: A Phase 2, Randomized, Double‐Blind, Placebo‐Controlled Trial

open access: yesArthritis &Rheumatology, EarlyView.
Objective An unmet need exists for glucocorticoid‐sparing treatments for patients with polymyalgia rheumatica (PMR). The antibody‐drug conjugate ABBV‐154 comprises adalimumab conjugated to a glucocorticoid receptor modulator. We evaluated ABBV‐154 versus placebo in patients with glucocorticoid‐dependent PMR.
Robert F. Spiera   +14 more
wiley   +1 more source

A systematic review of efficacy and safety of newer drugs approved from 2016 to 2023 for the treatment of complicated urinary tract infections

open access: yesAnnals of Medicine
Background: Complicated urinary tract infections are a significant cause of morbidity, hospitalization, and elevated hospital costs associated with kidney transplantations. The treatment of complicated urinary tract infections is very challenging, due to
Palanisamy Sivanandy   +8 more
doaj   +1 more source

Expert Perspective: How, When, and Why to Potentially Stop Antiresorptive Drugs in Osteoporosis

open access: yesArthritis &Rheumatology, EarlyView.
Osteoporosis is a chronic disease, and antiresorptive treatments are often continued for many years. Despite their established efficacy in reducing fracture risk, the most commonly used antiresorptive treatments, bisphosphonates and denosumab, have short‐ and long‐term risks that, coupled with their benefits and other unique characteristics, influence ...
Giovanni Adami, Kenneth G. Saag
wiley   +1 more source

Time‐Dependent Effect of Prophylactic Trimethoprim‐Sulfamethoxazole on the Incidence of Serious Infections in Antineutrophil Cytoplasmic Antibody–Associated Vasculitis: A Target Trial Emulation Study

open access: yesArthritis &Rheumatology, EarlyView.
Objective The objective of this study was to investigate the effect of prophylactic trimethoprim‐sulfamethoxazole (TMP‐SMX) on the incidence of serious infections in patients with antineutrophil cytoplasmic antibody–associated vasculitis (AAV). Methods This multicenter cohort study was designed to emulate a target trial that studied 296 patients with ...
Yun Kyu Kim   +7 more
wiley   +1 more source

A Comparison of Bacterial Colonies Count from Petri Dishes Utilizing Hough Transform and Traditional Manual Counting [PDF]

open access: yesarXiv
Bacterial colony enumeration is an essential stage in microbiological research, allowing susceptibility to antibiotics assessment, monitoring of the environment, and clinical diagnostics. Traditional manual counting methods are costly and susceptible to human mistakes, prompting the creation of automated detection systems.
arxiv  

Factors influencing physicians’ antimicrobial prescribing decisions: A systematic review of qualitative studies

open access: yesBritish Journal of Clinical Pharmacology, Volume 91, Issue 5, Page 1330-1351, May 2025.
Inappropriate and overuse of antimicrobials is increasing antimicrobial resistance. Understanding physicians' antimicrobial decision‐making is essential for developing interventions to optimize prescribing. The aim of this review was to identify the factors that influence physicians' antimicrobial prescribing decisions.
Savannah Reali   +4 more
wiley   +1 more source

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