Results 71 to 80 of about 596,047 (352)

Exploring urinary microbiome: insights into neurogenic bladder and improving management of urinary tract infections

Frontiers in Cellular and Infection Microbiology
The traditional view of sterile urine has been challenged by advancements in next-generation sequencing, revealing that the urinary microbiome significantly influences individual health and various urinary system diseases.
Jinming Zhang, Jinming Zhang, Yingyun Lei, Yingyun Lei, Huayong Du, Huayong Du, Zehui Li, Zehui Li, Xiaoxin Wang, Xiaoxin Wang, Degang Yang, Degang Yang, Feng Gao, Feng Gao, Jianjun Li, Jianjun Li   +15 more
doaj   +1 more source

FUNCTIONAL DIAGNOSTICS OF LOWER URINARY TRACT IN CHILDREN

Slovenska pediatrija, 2023
Lower urinary tract dysfunction is clinically relevant because it may cause urinary tract infections, mainly due to accumulation of residual urine, adversely affect renal function, and may cause urine incontinence that strongly affects the child’s ...
Matjaž Kopač, Anamarija Meglič
doaj   +1 more source

Multifunctional Bioactive Coatings Based on Bioglass, Vitamin D3, and Melittin Deposited via MAPLE for Enhanced Osseointegration, Antibacterial Activity, and Corrosion Resistance of Titanium Implants

Advanced Materials Interfaces, EarlyView.
Matrix‐Assisted Pulsed Laser Evaporation (MAPLE) technique is used to cover titanium (Ti) substrates with multifunctional bioactive coatings composed of bioglass, vitamin D3, and melittin. Coatings exhibited excellent chemical integrity and favorable micro/nanostructured morphology (promoting cellular adhesion and viability), and a sustained release of
Irina Negut, Bogdan Bita, Mihaela Dinu, Anca Constantina Parau, Tatiana Tozar, Oana Gherasim, Valentina Grumezescu, Carmen Ristoscu, Luminita Marutescu, Gratiela Gradisteanu Pircalabioru   +9 more
wiley   +1 more source

PVC Nanoplastics Exposure Exacerbates Asthma through R‐Loop Accumulation and Subsequent STING Activation in Macrophages

Advanced Science, EarlyView.
Polyvinyl chloride (PVC) nanoplastics (NPs) are shown to aggravate allergic airway inflammation in asthma by triggering R‐loop accumulation and activating the cGAS‐STING pathway in macrophages. This study reveals a novel immunotoxic mechanism linking environmental plastic exposure to asthma pathogenesis and highlights potential molecular targets for ...
Qimei Bao, Yixing Huang, Mingcong Deng, Chunkai Zhang, Dan Zu, Hanyi He, Yangchan Hu, Yuke Zhong, Chen Liang, Haidong Liu, Wumin Dai, Yanhua He, Yaoshu Teng, Ji Jing, Yin Shi, Xiangdong Cheng, Zu Ye   +16 more
wiley   +1 more source

Pharmacological Microglial Inhibition Remodels the Scar Microenvironment to Support Reticulospinal Circuit Reconstruction After Spinal Cord Injury

Advanced Science, EarlyView.
This study establishes pharmacological microglial inhibition as a therapeutic strategy, demonstrating its capacity to remodel the lesion microenvironment through significant reduction of extracellular matrix deposition. This permissive environmental transformation facilitates robust regeneration of the reticulospinal tract, and reconstructs functional ...
Run Li, Hongyuan Xing, Yifan Shen, Meng Chen, Bowen Lyu, Xiaofeng Yang, Li Sun, Chao Jiang, Jianyu Lv, Xin Ding, Zhongyang Gao, Yue Wang   +11 more
wiley   +1 more source

Clinical-microbiological characteristics of stationary urinary tract infections in capable people in conditions of north

Acta Biomedica Scientifica, 2013
Urgency of the research was determined by insufficiency of information in modern literature about microbiological structure antibiotic sensitivity of main pathogens of urinary tract infection among capable people in conditions of hospital. The aim.
V. N. Plekhanov
doaj  

A case of pyelonephritis and bacteremia caused by Candida glabrata in a patient on sodium glucose cotransporter 2 inhibitor, successfully treated with micafungin

Journal of Pharmaceutical Health Care and Sciences
Background Background factors for Candida spp. detection in urine include indwelling urinary catheters, diabetes mellitus, and a history of antimicrobial exposure; nevertheless, urinary tract infections caused by Candida spp.
Shoko Sahara, Teruhisa Kinoshita, Norio Takimoto, Keisuke Oka   +3 more
doaj   +1 more source

URINARY TRACT INFECTIONS IN PATIENTS WITH DIABETES. PART 2

Revista de la Sociedad Argentina de Diabetes, 2019
Urinary tract infections (UTIs) are frequent in daily medical practice. There are pathogenic factors that modulate the risk of their onset depending on the responsible germ and host.
María Florencia Aranguren, Barbara Arinovich, Teresa Bensusan, Guillermo De´Marziani, Gabriela Medek, Estrella Menéndez, María José Pomares, Jimena Soutelo, Fabiana Vázquez, Gloria Viñes   +9 more
doaj   +1 more source

Vaccines for the prevention of recurrent urinary tract infections: a systematic review

BJU International, 2018
To systematically review the evidence regarding the efficacy of vaccines or immunostimulants in reducing the recurrence rate of urinary tract infections (UTIs).
N. Aziminia, M. Hadjipavlou, Y. Philippou, S. Pandian, S. Malde, M. Hammadeh   +5 more
semanticscholar   +1 more source

KLK1 as an Epithelial‐Specific Brake Inhibits Colorectal Tumorigenesis by Suppressing B1R‐Mediated Fibroblast Phenotypic Transition

Advanced Science, EarlyView.
KLK1 downregulation disrupts the intestinal mucosal barrier and impairs kallikrein‐kinin signaling, thereby reducing Lys‐des‐Arg9‐BK production. This enhances B1R activation on ADAMDEC1⁺ fibroblasts, promoting inflammation and extracellular matrix (ECM) remodeling. The resulting iCAFs promote colorectal cancer progression, highlighting a novel KLK1‐B1R
Lisha Zhou, Meijing Wang, Shunji Liu, Limei Gu, Shijia Liu, Qianming Du, Tianyi Zhang, Yinuo Ma, Lixin Zhao, Jiaming Wang, Qiang Xu, Tingsheng Ling, Haibo Cheng, Hongqi Chen, Yang Sun   +14 more
wiley   +1 more source