Results 71 to 80 of about 1,350,711 (248)

Natural Product Toosendanin Suppresses the Malignant Development of Skin Melanoma by Targeting BNC2 for Degradation

open access: yesAdvanced Science, EarlyView.
BNC2 exhibits context‐dependent opposing functions across multiple cancer types. This study reveals BNC2 as an oncogenic driver of melanoma proliferation and metastasis through transcriptional activation of PIK3CA. The natural compound TSN simultaneously degrades BNC2 and its oncogenic partner SMAD3 via CRBN‐dependent ubiquitination.
Hui Dai   +7 more
wiley   +1 more source

Urinary tract infections [PDF]

open access: yes, 2023
Urinary tract infections are common bacterial infections that can occur in any part of the urinary system. The pathogens of urinary tract infections are usually bacteria that originate from the intestinal flora.
Cirpan, Rabiye
core   +1 more source

Regulation of poly-GlcNAc expression and fimbriation in uropathogenic "E. coli" [PDF]

open access: yes, 2013
The transition of planktonic to sessile lifestyles in bacteria rests upon a tightly controlled program that gets triggered by the environmental composition and whose implementation requires multiple feedback controls. Uropathogenic E.
Hosch, Lucie
core   +1 more source

Comparison of Minimally Invasive Colectomy Between Intra‐ Versus Extra‐Corporeal Anastomosis Technique (COMMIT Study): Short‐Term Analysis

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This multicenter propensity score‐matched study of 3213 patients compared intracorporeal (IA) and extracorporeal (EA) anastomosis during minimally invasive colectomy. IA was associated with a significantly lower incidence of intraoperative blood loss ≥ 200 mL (2.5% vs.
Takuya Takami   +9 more
wiley   +1 more source

Urinary tract infections: epidemiological and clinical aspects

open access: yes
Urinary tract infections are one of the most common infections affecting outpatients and hospital patients. They are believed to affect 150 million people annually and can present as an asymptomatic infection or infections of varying course and location.
Mariola Mendrycka   +2 more
core   +1 more source

Impact of Postoperative Infectious Complications on Long‐Term Survival After Curative Resection for Colorectal Cancer: A Multicenter Study in the Minimally Invasive Era

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Postoperative infectious complications (PICs) have been associated with poor long‐term outcomes after colorectal cancer surgery, but evidence in the modern minimally invasive era remains limited. In this multicenter cohort of 5377 patients undergoing curative resection, PICs were independently associated with worse overall survival and relapse‐free ...
Takehito Yamamoto   +7 more
wiley   +1 more source

The Relation between Treated Maternal Urinary Tract Infection and Adverse Maternal, Prenatal Outcomes in Pregnant Women of Ardabil, Iran [PDF]

open access: yes
Background and Objective: ­ Urinary tract infection is one of the most common bacterial infections during pregnancy and has also been implicated as a risk factor for adverse maternal and prenatal ­­outcomes.
مرادی, شهلا   +5 more
core  

Essential Updates in the Surgical Management of Inflammatory Bowel Disease: Current Topics From 2024 to Mid‐2026

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Inflammatory bowel disease management has undergone a major transformation with the introduction of treat‐to‐target strategies and highly effective biologic and small‐molecule therapies. Although these advances have reduced the overall requirement for surgery, operative intervention remains essential for selected patients with ulcerative ...
Yoshiki Okita   +4 more
wiley   +1 more source

Clinical-microbiological characteristics of stationary urinary tract infections in capable people in conditions of north

open access: yesActa Biomedica Scientifica, 2013
Urgency of the research was determined by insufficiency of information in modern literature about microbiological structure antibiotic sensitivity of main pathogens of urinary tract infection among capable people in conditions of hospital. The aim.
V. N. Plekhanov
doaj  

A case of pyelonephritis and bacteremia caused by Candida glabrata in a patient on sodium glucose cotransporter 2 inhibitor, successfully treated with micafungin

open access: yesJournal of Pharmaceutical Health Care and Sciences
Background Background factors for Candida spp. detection in urine include indwelling urinary catheters, diabetes mellitus, and a history of antimicrobial exposure; nevertheless, urinary tract infections caused by Candida spp.
Shoko Sahara   +3 more
doaj   +1 more source

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