Results 61 to 70 of about 2,834,545 (143)

sox17 Mutagenesis Reveals Compounding Effects ofMaternal and Zygotic Contribution on Microglia Abundance

open access: yesGlia, Volume 75, Issue 1, January 2027.
sox17 is a maternal effect gene impacting microglia and microglia precursor abundance. sox17 mRNA injection timed to maternal contribution rescues abundance. A CRISPR screen reveals f11r.1, gas6, and mpp1 also regulate microglia abundance. ABSTRACT Embryonic development is shaped by maternal and zygotic factors but how the interplay between these ...
Camden A. Spring   +4 more
wiley   +1 more source

RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging

open access: yesBiological Reviews, Volume 101, Issue 6, Page 2471-2500, December 2026.
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad   +5 more
wiley   +1 more source

Carrion ecology: concepts, interdisciplinary synthesis, and perspectives

open access: yesBiological Reviews, Volume 101, Issue 6, Page 2839-2873, December 2026.
ABSTRACT Carrion is a ubiquitous resource in both terrestrial and aquatic ecosystems, yet it has long been overlooked in ecological research. Over the past two decades, studies on carrion and the many organisms that exploit it have flourished, revealing not only wide‐ranging ecological functions but also significance far beyond ecology.
Marcos Moleón   +38 more
wiley   +1 more source

Effectiveness of Adding GLP‐1 Receptor Agonists to SGLT2 Inhibitor Therapy in Chronic Kidney Disease: A Population Based Study

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 12, Page 11755-11764, December 2026.
ABSTRACT Background Individually, sodium–glucose co‐transporter‐2 inhibitors (SGLT2i) and glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) have been shown to reduce major kidney and cardiovascular events in patients with chronic kidney disease (CKD). However, evidence supporting combined GLP‐1RA and SGLT2i therapy in this population remains limited.
Hussain Salim   +9 more
wiley   +1 more source

URINARY TRACT INFECTION IN WOMEN AGED 18-64: DOCTORS', PATIENTS’, AND LAY PERCEPTIONS AND UNDERSTANDINGS. [PDF]

open access: yes, 2012
This thesis provides an insight into the problems of urinary tract infection (UTI) through the eyes of women sufferers, non-sufferers, and health professionals. It describes the use of language and metaphor in women’s descriptions.
LARCOMBE, JAMES,HUGH   +1 more
core  

Eosinophilia and Hypereosinophilia: A Practical Approach to Navigating a Broad Differential Diagnosis

open access: yesEuropean Journal of Haematology, Volume 117, Issue 6, Page 1485-1499, December 2026.
ABSTRACT Eosinophilia, defined as an absolute eosinophil count (AEC) of ≥ 0.5 × 109/L, is a frequently encountered finding with a vast spectrum of potential underlying etiologies. Hypereosinophilia (HE) is defined as AEC > 1.5 × 109/L and may become life‐threatening when eosinophil‐induced organ damage occurs, defining the hypereosinophilic syndrome ...
Stijn Wigerinck, Peter Vandenberghe
wiley   +1 more source

Opioid Use and Family Members' Experiences of Opioids in Paediatric Cancer Pain Management: An Integrative Review

open access: yesScandinavian Journal of Caring Sciences, Volume 40, Issue 4, December 2026.
ABSTRACT Aim To analyse the use of opioids in children with cancer and the experiences of their family members regarding opioids used in pain management to improve family nursing. Design An integrative review. Methods A systematic literature search was carried out in four databases (CINAHL, MEDLINE, PsycInfo and Scopus) in August 2023, and was ...
Noora Puusa   +3 more
wiley   +1 more source

Dietary Interventions May Mitigate Health Risks of Per‐ and Polyfluoroalkyl Substances (PFAS) Exposure Through Modulation of the Gut Microbiota: A Review

open access: yesFood Frontiers, Volume 7, Issue 6, November 2026.
Dietary interventions, including probiotics, prebiotics, and synbiotics, may modulate gut microbiota to regulate PFAS accumulation and elimination. Specific microbial taxa facilitate PFAS removal through adsorption and bioaccumulation, potentially reducing internal PFAS burden and mitigating PFAS‐related health risks.
Jiahui Xia   +9 more
wiley   +1 more source

Antibiotic resistance patterns of urinary tract pathogens in children: current clinical challenges and therapeutic perspectives [PDF]

open access: yes
Urinary tract infections (UTIs) are common infections among children and are the most common proven bacterial infection in febrile infants without localising signs.
Gad, Safwat Hassan   +5 more
core   +1 more source

Soft Tissue Safety Assessment of Pulsed Solid‐State Thulium:YAG Versus Holmium:YAG Lasers: A Quantitative Porcine Model Simulation

open access: yesLasers in Surgery and Medicine, Volume 58, Issue 9, Page 811-820, November 2026.
ABSTRACT Objectives Laser lithotripsy carries an inevitable risk of collateral tissue injury. This study compared the safety profiles of pulsed Holmium:YAG and Thulium:YAG lasers by examining their effects on soft tissue under laser settings relevant to lithotripsy, using ex vivo porcine kidney models.
Dennis Buente   +4 more
wiley   +1 more source

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