Results 121 to 130 of about 4,735,402 (325)

Engineered Microfluidic Organoid Systems: New Paradigms for Menopause Mechanism Research and Personalized Medicine

open access: yesAdvanced Materials Technologies, EarlyView.
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang   +4 more
wiley   +1 more source

Microorganisms Identified in the Maternal Bladder: Discovery of the Maternal Bladder Microbiota

open access: yesAmerican Journal of Perinatology Reports, 2017
Objective The objective of this study was to characterize the bladder microbiota in pregnancy. Methods A prospective observational study of 51 pregnant women, admitted to a tertiary care hospital, who underwent straight catheterization urine
Kristin M. Jacobs   +4 more
doaj   +1 more source

Deep Convolutional Neural Networks Implementation for the Analysis of Urine Culture.

open access: yesClinical Chemistry, 2022
David J. Alouani   +5 more
semanticscholar   +1 more source

Early Radiation Therapy Response Assessment Using Multi‐Scale Photoacoustic Imaging

open access: yesAdvanced Science, EarlyView.
Tomographic and mesoscopic photoacoustics capture intratumoural features of radioresistance and response. ABSTRACT There is a critical unmet clinical need to identify biomarkers that predict and detect radiation therapy (RT) response in cancer. Using the unique capabilities of multi‐scale photoacoustic imaging (PAI) to depict tumor oxygenation and ...
Thierry L. Lefebvre   +12 more
wiley   +1 more source

Urinary Neutrophil Gelatinase-associated Lipocalin as a Marker for Identification of Acute Kidney Injury and Recovery in Dogs with Gentamicin-induced Nephrotoxicity. [PDF]

open access: yes, 2016
BackgroundAcute kidney injury (AKI) is associated with high mortality rates in dogs, which may be a consequence of late recognition using traditional diagnostic tests.
Cowgill, LD   +6 more
core   +2 more sources

Biodegradable Carbonate Nanogels Loaded with Anti MFAP‐5 siRNA for Anti‐stromal Therapy of Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
Polycarbonate nanogels enable lipid‐free delivery of anti‐MFAP‐5 siRNA into cancer‐associated fibroblasts (CAF) in hepatocellular carcinoma. In a cirrhotic murine model, this approach silences MFAP‐5, reduces fibroblast activation, and suppresses tumor growth by inhibiting NOTCH/Hes1‐driven angiogenesis. CAF‐targeted MFAP‐5 RNAi and conserved signaling
Paul Schneider   +20 more
wiley   +1 more source

Workflow Modifications and Addition of MALDI-TOF Technology Significantly Improved Turn-Around-Time to Identification of Common Urine Pathogens [PDF]

open access: yes, 2015
Background: In order to improve the identification of common aerobic urine cultures as well as antimicrobial susceptibility testing (AST) setup at an Academic Medical Center, work-flow modifications and MALDI-TOF technology were incorporated. Previously,
Alyemni, MD, Dimath   +2 more
core   +1 more source

Reflex urine culture testing in an ambulatory urology clinic: Implications for antibiotic stewardship in urology

open access: yesInternational journal of urology, 2018
To evaluate the performance characteristics of urinalysis and urine microscopy parameters for predicting urine culture results and to implement a reflex urine culture program.
K. Richards   +5 more
semanticscholar   +1 more source

PDZK1‐ULK1 Axis Triggers Lipophagy to Inhibit Tumor Progression and Sunitinib Resistance in Clear Cell Renal Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
This study reveals that PDZK1 loss impairs ULK1‐mediated lipophagy, driving lipid droplet accumulation and sunitinib resistance in clear cell renal cell carcinoma. PDZK1 inhibits LEF1 nuclear translocation, enhancing ULK1 transcription. Pharmacological ULK1 activation resensitizes resistant tumors to sunitinib.
Xuan Qi   +11 more
wiley   +1 more source

Update on Laboratory Diagnosis and Epidemiology of \u3cem\u3eTrichomonas vaginalis\u3c/em\u3e: You Can Teach an “Old” Dog “New” Trichs [PDF]

open access: yes, 2016
Past viewpoints on Trichomonas vaginalis infection have characterized the associated clinical disease as a “nuisance” condition, with affected demographics largely being older African American females residing in urban centers.
Munson, Erik   +2 more
core   +1 more source

Home - About - Disclaimer - Privacy