Results 121 to 130 of about 182,507 (249)

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Neurofilament light chain as in vitro and clinical biomarker of vincristine‐induced peripheral neuropathy

British Journal of Clinical Pharmacology, EarlyView.
Aims Vincristine‐induced peripheral neuropathy (VIPN) is a common side effect in children and adolescents treated with vincristine. Assessing VIPN, especially in young children, is challenging due to a lack of sensitive tools. This limits our understanding of the nature and risk factors of VIPN. This study aimed to investigate neurofilament light chain
Peter Erik Lotko Pontoppidan, Christian Bach Vase, Christina Mortensen, Liv Andres‐Jensen, Dorte Aalund Olsen, Jonna Skov Madsen, Kjeld Schmiegelow, Rene Mathiasen, Tore Bjerregaard Stage   +8 more
wiley   +1 more source

Impact of a structured urine culture request form on antimicrobial stewardship in urinary tract infections at a tertiary care hospital in India. [PDF]

Front Antibiot
Shettar SR, Sumana MN, Shetty MS, Maheshwarappa YD, Reddy R, Srinivasan A, Kalyatanda G, Gowda AG.   +7 more
europepmc   +1 more source

Biographies, ontological security and the socio‐spatial politics shaping teachers' mobility in remote Australia

British Educational Research Journal, EarlyView.
Abstract The global teacher shortage continues to intensify, with disparate impacts across geographic and socio‐economic communities. In Queensland, Australia, where this study originates, post‐COVID teacher shortages have intensified workforce pressures, leaving several regional, rural and remote schools as some of the ‘hardest‐to‐staff’ in the ...
Matthew Readette, Reece Mills, Terri Bourke, Simone White, Martin Mills, Lisa van Leent   +5 more
wiley   +1 more source

XGBoost (eXtreme Gradient Boosting) Can Predict Organisms Growing in Urine Culture from the Emergency Department. [PDF]

West J Emerg Med
Sheele JM, Campbell RL, Jones DD.
europepmc   +1 more source

Extracellular Vesicles‐Based Biological Macromolecule Delivery Systems: Biogenesis, Characterization, and Emerging Clinical Applications

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale membrane‐bound structures that play a pivotal role in intercellular communication by transporting bioactive molecules, including proteins, lipids, nucleic acids, and organelles, between cells. Originating from the endosomal pathway, EVs reflect the physiological and pathological status of their parent
Emine İncilay Torunoğlu, Zeynep Betül Sarı, Muhammed Emin Sarı, Erdi Can Aytar   +3 more
wiley   +1 more source

Patient and healthcare professionals' perceptions of educational tools to reduce urine culture contamination in outpatient clinics: a qualitative study. [PDF]

Antimicrob Steward Healthc Epidemiol
Collazo A, Haltom TM, Luna Rodriguez J, Olmeda K, Mancera A, Faustinella F, Paasche-Orlow MK, Landis-Lewis Z, Zoorob R, Trautner BW, Grigoryan L.   +10 more
europepmc   +1 more source

A novel biomimetic liposome drug delivery system mediated by macrophage targeting for precision treatment of encephalitis

BMEMat, EarlyView.
An advanced macrophage‐mediated biomimetic liposome (AC‐LP@RAW) that can penetrate the BBB and precisely target inflammatory sites in the deep brain was established in this study based on the unique immune homing property of macrophages, and showed a significantly improved delivery of curcumin to the brain.
Mengru Wu, Baoqin Song, Zhihao Chen, Wenzhong Li, Wanjun Liang, Xiu Wang   +5 more
wiley   +1 more source

Urine culture-guided antibiotic prophylaxis reduces febrile pyelonephritis after ureteral stent removal following radical cystectomy. [PDF]

World J Urol
Kitano H, Watanabe E, Tadera K, Nakano Y, Tasaka S, Yukihiro K, Okazaki M, Nomura N, Hatayama T, Shikuma H, Iwane K, Tasaka R, Kohada Y, Takemoto K, Miyamoto S, Naito M, Kobatake K, Sekino Y, Goto K, Goriki A, Hieda K, Hayashi T, Kashiyama S, Ohge H, Hinata N.   +24 more
europepmc   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source