Results 181 to 190 of about 77,909 (259)

A novel biomimetic liposome drug delivery system mediated by macrophage targeting for precision treatment of encephalitis

BMEMat, EarlyView.
An advanced macrophage‐mediated biomimetic liposome (AC‐LP@RAW) that can penetrate the BBB and precisely target inflammatory sites in the deep brain was established in this study based on the unique immune homing property of macrophages, and showed a significantly improved delivery of curcumin to the brain.
Mengru Wu, Baoqin Song, Zhihao Chen, Wenzhong Li, Wanjun Liang, Xiu Wang   +5 more
wiley   +1 more source

Acquired perforating dermatosis associated with uremic pruritus treated with dupilumab monotherapy: A case report. [PDF]

JAAD Case Rep
Mubarak S, AlEnezi H, AlKandari DI, Mosbeh AS, AlAlawi G.   +4 more
europepmc   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Determination of the half-life of di(2-ethylhexyl) phthalate (DEHP) in a preterm neonate using blood transfusion as the source of intravenous exposure. [PDF]

Curr Res Toxicol
Furlong M, Gupta V, Galanti S, Narasimhan S, Pulivarthi D, Andra SS, Stroustrup A.   +6 more
europepmc   +1 more source

Homologous membrane wrapped ZIF‐8 nanoparticles accelerate differentiation of neural stem cell for spinal cord injury therapy

BMEMat, EarlyView.
Homologous membrane wrapped ZIF‐8 nanoparticles were proposed to improve biocompatibility and targeting ability to neural stem cells (NSCs). ZIF‐8‐SCM NPs exhibit pH responsiveness, thereby generating an intracellular Zn2+ storm to accelerate neural differentiation through calcium and MAPK signaling pathways. Moreover, they promote function recovery in
Jie Wang, Lusen Shi, Xinhui Liu, Zhong Zhuang, Zhichao Feng, Chunhui Sun, Jingang Wang, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Shuping Wang, Hengxing Zhou, Na Ren   +11 more
wiley   +1 more source

Validation and evaluation of diagnostic tests for Schistosoma mansoni in Brazil: The ValidaXisto study protocol. [PDF]

PLoS One
Fonseca CT, da Silva-Pereira RA, Caldeira RL, Bernardes WPOS, Alves CC, Simões TC, Porto WJN, Oliveira EJ, ValidaXisto team.   +8 more
europepmc   +1 more source

A neuro‐behavioural model of neophobia

Biological Reviews, EarlyView.
ABSTRACT Fear can be defined as the internal neurological state that releases a repertoire of behaviours an animal performs to reduce the effect of an aversive factor. Neophobia, the fear of novelty, is a fundamental behavioural trait observed across a wide range of species from arthropods to humans.
Arik Dorfman, Aziz Subach, Inon Scharf
wiley   +1 more source

Advances in Human Mass Balance Studies: An IQ Consortium Perspective on Current Practices and Emerging Trends. [PDF]

Clin Pharmacol Ther
Boer J, Cannady E, Cuyckens F, Glaenzel U, Granvil C, Huth F, James AD, Li W, Veau C, Young G, Yue Q, Walker GS, Argikar UA, Bauman JN, Cantalloube C, Chen YL, Kang P, Moliner P, Pedersen ML, Piel I, Schadt S, Schieferstein H, Suchomel J, Wang S, Khojasteh SC.   +24 more
europepmc   +1 more source

Personalized Gamified Learning in a Course on the Urogenital System Anatomy: Differential Effects Across Learning Preference Profiles

Clinical Anatomy, EarlyView.
ABSTRACT Personalized learning approaches adapted to individual metacognitive characteristics have demonstrated promise in Anatomy education. However, whether such benefits are uniform across learner profiles or vary systematically remains an open question with implications for individualized instructional approaches.
Mónica Stambuk‐Castellano, Alejandro Ortega‐Arranz, Anna Carrera, Enrique Verdú, R. Shane Tubbs, Joe Iwanaga, Francisco Reina   +6 more
wiley   +1 more source

Unravelling the true biopsychosocial impact of schistosomiasis. [PDF]

Trends Parasitol
Osakunor DNM, Alonso S, Jumbe S, Lamberton PHL.   +3 more
europepmc   +1 more source