Results 31 to 40 of about 75,802 (261)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Identification and Characterization of Onchocerca volvulus Heat Shock Protein 70 (OvHSP70) as Novel Diagnostic Marker of Onchocerciasis in Human Urine

open access: yesPathogens
Despite several decades of mass drug administration and elimination-related activities, human onchocerciasis still represents a major parasitic threat in endemic regions.
Lum Abienwi Ambe   +12 more
doaj   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

Case Report: Application and Limitations of a Plant-Based Diet Formulated for a Cat With Feline Lower Urinary Tract Disease

open access: yesFrontiers in Veterinary Science, 2021
A 2-year-old male castrated domestic shorthair cat was presented for recommendations for dietary management of chronic FLUTD using a strictly plant-based diet as per the stipulations of the cat's owner.
Sarah A. S. Dodd   +4 more
doaj   +1 more source

The correlation between circulating antigen in urine and the intensity of Schistosoma haematobium infection [PDF]

open access: yesJournal of Medical and Life Science, 2020
Background: There are two methods for diagnosis of schistosomiasis, parasitological(microscopic detection of eggs), and/or immunological methods (antibody and antigen detection), due to the decreasing and elimination of Schistosomiasis infection in many ...
Ahmed Yameny
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Diuretic Effect of the Aqueous Extract of Cymbopogon nardus Compared with Furosemide in Wistar Rats

open access: yesTraditional and Integrative Medicine, 2023
Cymbopogon nardus is one of the medicinal plants widely used in folk medicine to cure certain diseases. The current work aims to assess the diuretic potential of Cymbopogon nardus using animal models.
Fatima El Kamari   +7 more
doaj   +1 more source

Clinical Validation of Plasma p‐217tau in Neurological Diseases

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi   +13 more
wiley   +1 more source

Post-exercise rehydration with coconut water: as effective as a sports drink, or better?

open access: yesMHSalud, 2011
Objective: To compare the effectiveness of fresh coconut water as a rehydration beverage with bottled water and a sports drink. Method: eleven participants, 22.0±1.9 years of age and 65.6±13.0 kg body mass (average ± S.D.), reported to the laboratory on
Alexandra Pérez Idárraga   +1 more
doaj  

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