Results 91 to 100 of about 17,093 (208)

Chronic idiopathic urinary retention and Fowler's syndrome in women: A multidisciplinary framework for assessment and nonsurgical management

BJUI Compass, Volume 7, Issue 7, July 2026.
Abstract Chronic idiopathic urinary retention and Fowler's syndrome are a debilitating problem primarily affecting women, characterised by an inability to urinate in the absence of any identifiable structural or other cause. An increasingly wide range of multifactorial predisposing, precipitating, and perpetuating biopsychosocial factors are being ...
Sarah McRae, Caoimhe McLoughlin, Carolyn Davie, Claire Hentzen, Dani Coombe, Claire Todd, Clare Nicholson, Beatrice Garcin, Glenn Nielsen, Helen Simpson, Laura McWhirter, Helen Jinadu, Jalesh Panicker, Anne Sanderson, Alan Carson, Martine Cornillet, Miriam Gamble, Voula Granitsiosis, Sioned Hancock, Collete Haslam, Leila Heelas, Victoria Hulman, Emily Jay, Mahreen Pakzad, Caroline Selai, Natalia Vasquez, Louise Young, Jon Stone, Ingrid Hoeritzauer   +28 more
wiley   +1 more source

Pharmacokinetics, safety, tolerability and fluorescence imaging of nizaracianine triflutate administered in three divided doses to healthy volunteers

British Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 2085-2094, July 2026.
Aim Fluorescence‐guided surgery enhances intraoperative visualization of anatomical structures. Nizaracianine is a near‐infrared fluorescent agent that is exclusively renally cleared in animal models. It enables real‐time ureteral imaging and identification, potentially reduces risk of injury and facilitates assessment before surgical closure.
Lisanne K. A. Neijenhuis, Cedric M. W. Pesch, John V. Frangioni, Alexander L. Vahrmeijer, Jacobus Burggraaf, Naomi B. Klarenbeek   +5 more
wiley   +1 more source

Proposal of a Risk Stratification Algorithm for Extracranial Malignant Rhabdoid Tumors

Cancer Medicine, Volume 15, Issue 7, July 2026.
ABSTRACT Background Malignant rhabdoid tumors (MRT) are highly aggressive tumors, primarily described in children, but also affecting adults. The objective was to identify independent prognostic factors to predict individual patients' risk and to establish an age‐spanning risk stratification system for prospective trials. Patients and Methods Data from
Juno Eberl, Angelika Eggert, Monika Scheer   +2 more
wiley   +1 more source

Multiparametric Ultrasound Findings of Testicular Sarcoidosis

Journal of Ultrasound in Medicine, Volume 45, Issue 7, Page 1497-1504, July 2026.
Objectives To characterize the multiparametric ultrasound (MPUS) features of testicular sarcoidosis, incorporating greyscale, color Doppler ultrasound (CDUS), contrast‐enhanced ultrasound (CEUS), and strain elastography (SE), and to assess their collective diagnostic value.
Huahui Liu, Razan Abudalo, Ghali Salahia, Gibran T. Yusuf, Dean Y. Huang, Paul S. Sidhu   +5 more
wiley   +1 more source

Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?

Medicinal Research Reviews, Volume 46, Issue 4, Page 1111-1151, July 2026.
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca, Mariana Feijó, Cátia V. Vaz, Bruno J. Pereira, Sandra Laurentino, Ana Palmeira‐de‐Oliveira, Sílvia Socorro   +6 more
wiley   +1 more source

A Primate‐Specific lncRNA LINC01021 Contributes to Cellular and Organismal Aging via DAZAP1‐Dependent Destabilization of RBMX

Aging Cell, Volume 25, Issue 7, July 2026.
Primate‐specific lncRNA LINC01021 promotes aging by enhancing cellular senescence and accelerating aspects of organismal decline. Mechanistically, LINC01021 induces DAZAP1‐mediated destabilization of RBMX, activating the P53 pathway and establishing a primate‐specific regulatory axis in aging.
Yan Zhang, Li Hu, Xin Dong, Qinghua Zeng, Meiting Zi, Ayesha Nisar, Sawar Khan, Raoxian Bai, Chonghui Liu, Mingxia Ge, Shaoyan Pu, Gonghua Li, Yonghan He   +12 more
wiley   +1 more source

Systematic Characterization of Splicing Dysregulation in Pan Solid Tumor Transcriptome

Advanced Science
Splicing dysregulation arising from spliceosomal mutations contributes to disease progression and treatment resistance, mostly in hematologic malignancy. Whereas spliceosomal mutations are less common in solid tumors, splicing disorders are pervasive and
Jingru Sui, Dan Guo, Xiao Wen, Lei Zhou, Yue Huang, Haoyu Yu, Jinyu Chen, Zhaoqi Liu   +7 more
doaj   +1 more source

Long‐term outcomes following a 5‐year recurrence‐free interval in non‐muscle‐invasive bladder cancer

BJU International, Volume 138, Issue 1, Page 125-132, July 2026.
Objective To describe the recurrence and progression trends of non‐muscle‐invasive bladder cancer (NMIBC) during a 14‐year period in Denmark between 2009 and 2022. Furthermore, to evaluate the risk of late recurrence with or without progression in patients who initially experience a 5‐year recurrence‐free interval (RFI).
Peter B. Hjort, Jørgen B. Jensen, Andreas Ernst   +2 more
wiley   +1 more source

Homozygous Loss‐of‐Function Variant in SLC20A1 Coding for Ubiquitous Phosphate Transporter PiT1 Is Associated With Multiple Developmental Abnormalities

Clinical Genetics, Volume 110, Issue 1, Page 64-72, July 2026.
Biallelic SLC20A1 loss‐of‐function variant causes a previously unrecognized multisystem developmental disorder. We report the first homozygous case presenting with tetralogy of Fallot, renal agenesis, polydactyly, and growth impairment. Transcriptome analysis of patient‐derived fibroblasts suggests significant dysregulation of pathways critical for ...
Eugénie Koumakis, Céline Huber, Wendy Chung, Christine Leroy, Pauline Parisot, Regis Gaudin, Mohamad Zaidan, Valérie Cormier‐Daire, Gérard Friedlander, Yoel Hirsch   +9 more
wiley   +1 more source

Preclinical and Virtual Models of Mucosal Melanoma: Bridging Translational Gaps in a Rare and Lethal Cancer

Pigment Cell &Melanoma Research, Volume 39, Issue 4, July 2026.
Integrated physical and virtual modeling provides a scalable framework to overcome sample scarcity, recapitulate mucosal melanoma biology, and accelerate translational discovery toward precision medicine. ABSTRACT Mucosal melanoma (MM) is a rare and lethal subtype of melanoma, disproportionately affecting Asian populations and exhibiting distinct ...
Xiangjie Jin, Yuhan Zhang, Yuantai Zhu, Zhiyuan Zhang, Chaoji Shi   +4 more
wiley   +1 more source