Results 121 to 130 of about 13,757 (279)

PARP Inhibitors in Genitourinary Cancer: A New Paradigm Beyond Prostate Cancer

International Journal of Urology, EarlyView.
ABSTRACT Alterations in the homologous recombination repair genes, such as BRCA1 and BRCA2, are prevalent in various cancers, presenting a unique opportunity to develop synthetic lethal strategies that target homologous recombination deficiency (HRD).
Yohei Okuda, Taigo Kato, Yu Ishizuya, Takuji Hayashi, Yoshiyuki Yamamoto, Koji Hatano, Atsunari Kawashima, Junko Murai, Norio Nonomura   +8 more
wiley   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source

Urogenital History in Veterans Exposed to High-Dose Sulfur Mustard: A Preliminary Study of Self-Reported Data

Urology Journal, 2009
<p><strong>Introduction: </strong>To date, little information exists regarding urogenital diseases in those who have been exposed to sulfur mustard (SM).
Mohammad Reza Soroush, Mostafa Ghanei, Shervin Assari, Hamid Reza Khoddami Vishteh   +3 more
doaj  

Cholecystokinin: Clinical aspects of the new biology

Journal of Internal Medicine, EarlyView.
Abstract Cholecystokinin (CCK) is a classic gut hormone that has been known for almost a century to regulate gallbladder emptying, pancreatic enzyme secretion, and gastrointestinal motor activity. In 1968, the CCK structure was identified by Viktor Mutt and Erik Jorpes from porcine gut extracts as a peptide of 33 amino acid residues.
Jens F. Rehfeld
wiley   +1 more source

Are Nursing Students’ Thesis Topics in Accordance with Burden of Diseases as Disability Adjusted Life Years in Iran? [PDF]

مجله ایرانی آموزش در علوم پزشکی, 2006
Introduction: Research is the basis of nursing and should be in accordance with society’s health needs. The purpose of this study was to determine whether the master theses’ subjects in nursing conform to the burden of diseases as Disability Adjusted ...
Khadijeh Heravi Karimooi, Fereshteh Aein, Fazloallah Ahmadi, Mina Tootoonchi   +3 more
doaj  

Relationship between periodontitis and systemic diseases: A bibliometric and visual study

Periodontology 2000, EarlyView.
Abstract To provide a comprehensive and updated mapping of observational studies assessing the relationship between periodontitis and systemic diseases through a bibliometric and visual analysis. A search was conducted using the Web of Science database, covering the period 1989 to 2024.
Gaetano Isola, Alessandro Polizzi, Sara Serra, Mattia Boato, Anton Sculean   +4 more
wiley   +1 more source

Genomic Evaluation of Canine Prostatic Carcinomas as a Model for the Human Disease: or ‘UC or not UC – that is the question’

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Spontaneous canine prostate cancer (PC) is widely considered a pertinent clinical model for the human disease. While over 95% of PC in men are adenocarcinomas, arising from prostatic glandular epithelium, it is increasingly recognised that many canine PC are of urothelial origin, arising within the prostatic urethra or ducts, or through ...
Rachael Thomas, Jennifer A. Luff, Allison N. Dickey, Megan N. Dillon, Isabella G. Livingston, Carter A. Schrag, Steven E. Suter, Matthew Breen   +7 more
wiley   +1 more source

Germ cell and other tumors in individuals with differences in sex development

CA: A Cancer Journal for Clinicians, EarlyView.
Abstract Approximately one in 3500 to one in 5100 live‐born infants have atypical external genital development, known as differences in sex development (DSD). In 2005, an expert consensus conference thoroughly reviewed aspects of health care for individuals with DSD.
Selma Feldman Witchel, Miguel Reyes‐Múgica   +1 more
wiley   +1 more source

The Role of Glycoprotein Non‐Metastatic Melanoma Protein B (GPNMB) in Tumors and Other Diseases

MedComm – Oncology, Volume 4, Issue 3, September 2025.
Glycoprotein non‐metastatic melanoma protein B (GPNMB) is is widely involved in biological processes such as tissues, cells, metabolism and immunity, regulates multiple signaling pathways, and plays an important role in the occurrence and development of various diseases, including tumors.
Zhenyu Wu, Na Sun, Man Qu, Xia Kang, Yi Zhang, Xiaowei Qi   +5 more
wiley   +1 more source

The new approaches to problem of polymorbidity [PDF]

, 2014
High prevalence of polymorbidity in outpatient therapeutic practice calls for improvement of diagnostic approaches, in particular, the development of methods for its measurement and using the results for optimization the number of medical, rehabilitation,
Tkhorikova, V. N., Zhuravlev, Y. I.
core   +1 more source