Results 131 to 140 of about 330,537 (279)

Abnormal DNA Methylation Profile Suggests the Extension of the Clinical Spectrum of the SETD2 ‐Related Disorders to a Syndromic Multiple Tumor Phenotype

American Journal of Medical Genetics Part A, Volume 197, Issue 7, July 2025.
ABSTRACT SETD2 has an essential role in epigenetic regulation. SETD2 pathogenic variants cause neurodevelopmental disorders (SETD2‐NDDs) that most commonly include various degrees of intellectual disability and behavioral disorders, macrocephaly, brain malformations, and generalized overgrowth.
Marie Lucain, Antonio Vitobello, Bekim Sadikovic, Juliette Albuisson, Léa Gaudillat, Martin Chevarin, Julien Maraval, Christel Thauvin‐Robinet, Jennifer Kerkhof, Christophe Philippe, Sophie Nambot, Laurence Faivre   +11 more
wiley   +1 more source

Angiogenesis inhibition by green propolis and the angiogenic effect of L-lysine on bladder cancer in rats Inibição da angiogênese pela própolis verde e efeito angiogênico da L-lisina no câncer de bexiga em ratos

Acta Cirúrgica Brasileira, 2012
PURPOSE: To determine the effects of water-soluble derivative of green propolis in bladder cancer angiogenesis in rats given N-butyl-(-4-hydroxybutyl) nitrosamine (BBN).
Conceição Aparecida Dornelas, Francisco Vagnaldo Fechine-Jamacaru, Irineu Lima Albuquerque, Hemerson Iury Ferreira Magalhães, Thiago Alves Dias, Mário Henrique Girão Faria, Markênia Kely Santos Alves, Silvia Helena Barem Rabenhorst, Paulo Roberto Carvalho de Almeida, Telma Leda Gomes de Lemos, José Daniel Vieira de Castro, Maria Elisabete Amaral Moraes, Manoel Odorico Moraes   +12 more
doaj   +1 more source

GATA Transcription Factors: A Cross‐Road for Erythropoiesis, Neurodevelopment, and Synucleinopathies

Developmental Neurobiology, Volume 85, Issue 3, July 2025.
ABSTRACT Alpha‐synuclein (α‐syn), a 140 amino acid protein, is abundantly expressed in the central nervous system (CNS) and in the erythrocytes, playing a pivotal role in the pathogenesis of Parkinson's disease (PD) and other synucleinopathies.
Francesco Bellomi, Claudia Caturano, Viola Velardi, Romina Mancinelli, Simone Carotti, Giorgio Vivacqua, Francesca Arciprete, Maria Zingariello   +7 more
wiley   +1 more source

Retrospective study: Laser excision versus combined laser, cryosurgery and intralesional 5‐fluorouracil in the treatment of equine sarcoids

Equine Veterinary Education, Volume 37, Issue 7, Page 353-362, July 2025.
Summary Background Laser excision is used routinely in the treatment of sarcoids but may be ineffective in cases where complete excision cannot be achieved. A multimodal approach is warranted in these cases. 5‐FU may improve the lethal effect of cryosurgery as an adjunct to laser excision.
Katie S. Offer, David G. M. Sutton
wiley   +1 more source

2023 Korean sexually transmitted infections guidelines by the Korean Association of Urogenital Tract Infection and Inflammation: Human papillomavirus vaccination [PDF]

Investigative and Clinical Urology
The Korean Association of Urogenital Tract Infection and Inflammation (KAUTII) and the Korea Disease Control and Prevention Agency updated the guidelines for human papillomavirus (HPV) vaccine against sexually transmitted HPV infections in Korea to ...
Chang Il Choi, Seung-Ju Lee, Jin Bong Choi, Tae-Hyoung Kim, Jeong Woo Lee, Jun Mo Kim, Sangrak Bae   +6 more
doaj   +1 more source

Ultrasonographic Appearance of the Deferent Ducts in Dogs without Genitourinary Disease

Veterinary Radiology &Ultrasound, Volume 66, Issue 4, July 2025.
ABSTRACT In veterinary medicine, deferent ducts are described as being visible on ultrasound only when pathologically enlarged. Abnormal ultrasonographic enlargement of the deferent ducts has primarily been described secondary to infectious and neoplastic diseases; however, no studies have evaluated the normal ultrasonographic features of these ...
Anna Palomares, Yvonne Espada, Mauricio Tobón Restrepo, Sonia González‐Rellán, Rosa Novellas   +4 more
wiley   +1 more source

An Analysis of Clinical Questions Asked at Professor Rounds: A Ten-Year Review of Topics [PDF]

, 2014
Questions asked at residents’ educational conferences can be valuable catalysts for learning. Although finding answers to these queries is the ultimate goal, the topics of these questions themselves can be equally instructive.
Bianchi, Nancy A.
core   +1 more source

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

Molecular Oncology, Volume 19, Issue 6, Page 1668-1686, June 2025.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu, Jinqiu Li, Junqi Ma, Ayshamgul Hasim   +3 more
wiley   +1 more source

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

Molecular Oncology, Volume 19, Issue 6, Page 1811-1835, June 2025.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

Molecular Oncology, Volume 19, Issue 6, Page 1651-1667, June 2025.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien, Marta E. Hjelmeland, Hege F. Berg, Rose M. Gold, Kathrine Woie, Lars A. Akslen, Ingfrid S. Haldorsen, Camilla Krakstad   +7 more
wiley   +1 more source