Results 41 to 50 of about 198 (173)

Hypervision Proton Surgery: The Future Direction of Proton Therapy

iNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source

Urban relatives ameliorate survival disparities for genitourinary cancer in rural patients

Cancer Medicine
Introduction Patients living in rural areas have worse cancer‐specific outcomes. This study examines the effect of family‐based social capital on genitourinary cancer survival.
Mouneeb Choudry, Kassandra Dindinger‐Hill, Jacob Ambrose, Joshua Horns, Jeffrey Vehawn, Hailie Gill, Nicole Z. Murray, Trevor C. Hunt, Christopher Martin, Benjamin Haaland, Jonathan Chipman, Heidi A. Hanson, Brock B. O'Neil   +12 more
doaj   +1 more source

Organ‐Specific Human Microbiomes and Dysbiosis: Mechanistic Links to Disease and Emerging Therapeutic Strategies

Journal of Clinical Laboratory Analysis, EarlyView.
Schematic overview of the human microbiome and major microbiota‐derived metabolites across body sites, highlighting the gut–brain, gut–heart, and gut–kidney axes in host physiology and disease. ABSTRACT Background The human microbiome is a dynamic and diverse community of microorganisms that affects susceptibility to illness and promotes wellness ...
Awadh Alanazi
wiley   +1 more source

Symptoms and signs of urogenital cancer in primary care

BMC Primary Care, 2023
Background Urogenital cancers are common, accounting for approximately 20% of cancer incidence globally. Cancers belonging to the same organ system often present with similar symptoms, making initial management challenging.
Knut Holtedahl, Lars Borgquist, Gé A. Donker, Frank Buntinx, David Weller, Christine Campbell, Jörgen Månsson, Victoria Hammersley, Tonje Braaten, Ranjan Parajuli   +9 more
doaj   +1 more source

The silence of mitotic figures

Patient Experience Journal, 2023
A career in medicine is guided by the patients you treat and those who have taught you to treat these individuals. Communication is of utmost importance in all aspects of healthcare. However, there are times when communication can be difficult.
Hope K Haefner
doaj   +1 more source

Human Umbilical Cord Mesenchymal Stem Cell–Derived Exosomes Attenuate Renal Fibrosis by Suppressing Fibroblast Activation via the INHBA/PI3K/AKT Pathway

Pediatric Discovery, EarlyView.
MSC‐Exo derived from human umbilical cord (HucMSC‐Exo) downregulates INHBA expression, consequently modulating the PI3K/AKT signaling cascade. This regulation attenuates renal fibroblast activation and extracellular matrix deposition, thereby exerting a renoprotective effect against fibrosis.
Meiling Chen, Chenxi Jia, Zhuocheng Shi, Bianan Zhu, Yihang Yu, Xing Liu, Feng Liu, Jianwei Chen, Tao Xu, Yuanyuan Zhang, Deying Zhang, Guanghui Wei   +11 more
wiley   +1 more source

MicroRNA‐130a‐3p Targets the Androgen‐Related Transcription Factor MAFB: Effects on Proliferation, Migration, Apoptosis, and Cell Cycle in Hypospadias

Pediatric Discovery, EarlyView.
MicroRNA‐130a‐3p targets and inhibits MAFB expression, leading to the development of hypospadimas. MicroRNA‐130a‐3p inhibits the expression of MAFB, disrupts the normal processes of cell proliferation, migration, cell apoptosis, and cycle progression, and ultimately leads to the development of hypospadias.
Jiaxin Zhou, Yixuan Wang, Zhicheng Zhang, Qiang Zhang, Zhenmin Liu, Hongsong Chen, Xingguo Luo, Chunlan Long, Lianju Shen, Xing Liu, Guanghui Wei   +10 more
wiley   +1 more source

Management of De Novo miN1 Prostate Cancer in the PSMA‐PET Era

The Prostate, EarlyView.
ABSTRACT Background Prostate‐specific membrane antigen positron emission tomography (PSMA‐PET) is reshaping nodal staging in prostate cancer by detecting regional lymph node metastases with greater accuracy than conventional imaging. This has created a new cohort of patients with N1M0 disease detectable only on advanced imaging, raising important ...
Thomas McMaster, Caitlin Ying Ming Louey, Jordan Santucci, Chloe Hobson, David D. Chen, Niranjan Sathianathen, Joseph Ischia, Damien M. Bolton, Nathan Lawrentschuck, Declan G. Murphy, Shankar Siva, Marlon Perera   +11 more
wiley   +1 more source

Low albumin-to-creatinine ratios (ACR) are associated with poor outcomes in cancer patients

BMC Cancer
Background The albumin-to-creatinine ratio (ACR) is known to predict prognosis in liposarcoma patients, but its role in other tumors remains unclear. This study aimed to evaluate the prognostic relationship between ACR and common solid tumors.
Hong Zhao, Xiangrui Li, Xiaoyue Liu, Chenan Liu, Xin Zheng, Yue Chen, Jinyu Shi, Qiteng Liu, Zhaoting Bu, Hanping Shi   +9 more
doaj   +1 more source

Head‐to‐head prospective comparison of diagnostic accuracy of preoperative ultrasonography and MRI in patients undergoing surgery for deep endometriosis using #Enzian classification

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective To perform a head‐to‐head comparison of the diagnostic performance of ultrasonography (US) vs magnetic resonance imaging (MRI) for the preoperative detection of endometriosis using the #Enzian classification system. Methods This was a prospective observational study of postmenarchal premenopausal women who underwent laparoscopy ...
B. Pete, K. Turtóczki, A. Bokor, I. Kalina, I. Madár, L. Lipták, J. Rigó Jr, N. Ács, G. Szabó   +8 more
wiley   +1 more source