Results 261 to 270 of about 22,585,443 (353)

Effectiveness and Toxicity of Anticancer Agents in Older Australian Patients: A Retrospective Analysis

open access: yesAsia-Pacific Journal of Clinical Oncology, Volume 21, Issue 6, Page 616-622, December 2025.
We conducted a retrospective observational analysis of patients ≥75 years. To our knowledge, this is the first study providing real‐world data on the efficacy, and safety, of anti‐cancer agents in older patients in a regional Australian center across multiple tumor streams.
Joseph S. Taylor   +4 more
wiley   +1 more source

Antimicrobial prescribing guidelines for horses in Australia

open access: yesAustralian Veterinary Journal, Volume 103, Issue 12, Page 781-889, December 2025.
The growing problem of antimicrobial resistance also affects equine veterinarians with increasing frequency. Antimicrobial stewardship and responsible prescribing are essential for a future in which effective antimicrobials are available, as it is unlikely that new antimicrobials will become available for use in horses.
L Hardefeldt   +18 more
wiley   +1 more source

TRPA1 ion channel activation context‐dependently regulates gene expression in normal and psoriatic human skin

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 23, Page 5814-5825, December 2025.
Abstract Background and Purpose Psoriasis is a chronic, relapsing, immune‐mediated inflammatory skin disease. The transient receptor potential ankyrin 1 (TRPA1) ion channel plays a protective role in the formation of psoriasiform skin reactions. Here, we investigated the pharmacological activation and blockade of TRPA1 in human skin (patho)physiology ...
Ágnes Kemény   +10 more
wiley   +1 more source

Sodium‐Glucose Cotransporter 2 Inhibitors Use and Adverse Kidney Outcomes in Patients Receiving Contrast Media

open access: yesClinical and Translational Science, Volume 18, Issue 12, December 2025.
ABSTRACT The kidney benefits of sodium‐glucose cotransporter‐2 inhibitors (SGLT2i) in patients receiving contrast media remain unclear. This Taiwanese cohort study investigated the short‐ and long‐term effects of SGLT2i on adverse kidney outcomes in patients receiving contrast media between January 1, 2016 and December 31, 2018.
Lung‐Chih Li   +4 more
wiley   +1 more source

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