Status quo and future developments in the diagnosis and treatment of hereditary angioedema
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 12, Page 1512-1525, December 2025.Summary Hereditary angioedema (HAE) is a rare hereditary disease characterized by edema, which can be life‐threatening in case of swelling in the larynx. The most common form of HAE is caused by a mutation of the SERPING1 gene and is characterized by a deficiency (type I) or loss of function (type II) of the C1 inhibitor (C1‐INH), leading to excessive ...
Andreas Recke
wiley +1 more source
De Novo Myeloid Sarcoma of the Kidney: A Case Report and Literature Review of Clinical Features and Outcomes. [PDF]
CureusXiong J +6 more
europepmc +1 more source
The Early Development of the Blue‐Eye Cichlid, Cryptoheros spilurus (Cichliformes: Cichlidae)
Evolution &Development, Volume 27, Issue 4, December 2025.We document the early development of Cryptoheros spilurus, highlighting rapid cranial differentiation, sensory organ formation, and fin development. Ontogenetic allometry and ultrastructural traits reveal functional adaptations for early foraging and locomotion, offering insights into ecological success and the developmental basis of cichlid ...
Rubén Alonso Contreras‐Tapia +5 more
wiley +1 more source
Epithelial cell shape changes contribute to regulation of ureteric bud branching morphogenesis
The FEBS Journal, Volume 292, Issue 23, Page 6253-6282, December 2025.Ureteric bud (UB) branching determines the final size, shape, and nephron number of kidneys. Characterization of UB cell shapes identified dynamic round‐to‐elliptical transitions and cellular volume changes as critical epithelial modifications that increase morphological complexity in UB tips during their transitions through ampulla‐to‐asymmetric ...
Kristen Kurtzeborn +9 more
wiley +1 more source
Molecular Genetics of Primary Congenital Hypothyroidism: Established and Emerging Contributors to Thyroid Dysgenesis. [PDF]
Int J Mol SciDermitzaki N +6 more
europepmc +1 more source
The FEBS Journal, Volume 292, Issue 23, Page 6182-6194, December 2025.Enzymes from the phosphodiesterase type 4 family (PDE4) coordinate physiological events driven by the cyclic AMP s(cAMP) signaling pathway by tightly controlling cAMP dynamics in many cell types. Key to this strict regulation is the myriad of posttranslational modifications that alter PDE4 activity, cellular location, and binding partner selection ...
Madihah Hussain +2 more
wiley +1 more source
Veterinary and Comparative Oncology, Volume 23, Issue 4, Page 528-548, December 2025.ABSTRACT Spontaneous canine prostate cancer (PC) is widely considered a pertinent clinical model for the human disease. While over 95% of PC in men are adenocarcinomas, arising from prostatic glandular epithelium, it is increasingly recognised that many canine PC are of urothelial origin, arising within the prostatic urethra or ducts, or through ...
Rachael Thomas +7 more
wiley +1 more source
From Mesh to Modern Therapies: An Updated Narrative Review on Urogenital Prolapse. [PDF]
J Clin MedPop-Lodromanean D +6 more
europepmc +1 more source
EFSA Journal, Volume 23, Issue 12, December 2025.Abstract According to the ‘EFSA‐SANTE Action Plan on Cumulative Risk Assessment for pesticides residues’, EFSA, with the support of a working group, undertook the identification of specific effects on male and female reproductive function, including fertility, that are considered relevant for grouping pesticide residues and for assessing ...
European Food Safety Authority (EFSA) +10 more
wiley +1 more source
Determinants of urogenital tract infection symptoms among adolescent girls and young women in secondary schools and universities in Bukavu, Democratic Republic of Congo: a cross-sectional study. [PDF]
BMC Womens HealthMaroyi R +8 more
europepmc +1 more source