Results 21 to 30 of about 24,773 (192)

SIRT5‐Mediated Desuccinylation of ACAA2 Protects Against Calcium Oxalate‐Induced Kidney Injury by Regulating Fatty Acid Oxidation to Suppress Mitochondrial Oxidative Injury and Ferroptosis

Advanced Science, EarlyView.
The SIRT5/ACAA2 axis maintains lipid metabolic homeostasis in RTECs by promoting ACAA2 desuccinylation and preserving its stability and enzymatic activity, thereby sustaining FAO and limiting PUFA and PUFA‐containing phospholipid accumulation. Under CaOx stress, SIRT5 downregulation impairs FAO, promotes oxidative stress and ferroptosis, and enhances ...
Qinhong Jiang, Caitao Dong, Yuchen Liu, Yuanquan Lou, Wenlong Lin, Sheng Li, Ziqi He   +6 more
wiley   +1 more source

Urogenital Infection Risk Associated With SGLT2 Inhibitors Versus DPP‐4 Inhibitors in Type 2 Diabetes and Chronic Kidney Disease: A Nationwide Target Trial Emulation

Clinical Pharmacology &Therapeutics, EarlyView.
Although sodium‐glucose cotransporter‐2 inhibitors (SGLT2i) are recommended for patients with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD), concerns regarding urogenital infections persist. Therefore, we evaluated the risk of urinary tract infection (UTI) and genital tract infection (GTI) after SGLT2i initiation in this population ...
Young‐Mi Ah, Junsung Nam, Jung Wook Youn, Yun Mi Yu, Soyoung Kang   +4 more
wiley   +1 more source

The relationship between uric acid and dyslipidemia in type 2 diabetic patients with urolithiasis

Baghdad Journal of Biochemistry and Applied Biological Sciences, 2022
Background and objectives: Type 2 diabetes mellitus (DM) is characterized by insulin resistance, which can increase the risk of kidney stone formation.
Dona Devasia, V Nimisha
doaj   +1 more source

Mapping the Landscape of Over‐Scanning in CT Imaging: A Scoping Review

Journal of Medical Radiation Sciences, EarlyView.
Over‐scanning in CT is highly prevalent and contributes to unnecessary radiation exposure, with notable impact on radiosensitive organs. Standardised protocols and AI‐assisted planning show strong potential to optimise scan range and reduce excess dose.
Mo'men Bani‐Ahmad, Aoife O Sullivan, Yasser H. Hadi, Laura McLaughlin, Andrew England, Mark McEntee   +5 more
wiley   +1 more source

Comparison of p‐Tm:YAG, TFL and Ho:YAG's in vitro ablation rates on synthetic and human stones

BJUI Compass
Objective To compare in vitro the ablation rates of p‐Tm:YAG, TFL and Ho:YAG against synthetic and human stones. Material and Methods p‐Tm:YAG, TFL and Low‐Power (LP) Ho:YAG were compared using 270 μm core‐diameter laser fibres (CDF); experiments with ...
Frédéric Panthier, Alba Sierra, Etienne Xavier Keller, Marie Chicaud, Eugenio Ventimiglia, Jia‐Lun Kwok, Vincent De Coninck, Mariela Corrales, Michel Daudon, Cyril Gorny, Steeve Doizi, Laurent Berthe, Daron Smith, Olivier Traxer   +13 more
doaj   +1 more source

The association between a non-invasive hepatic fibrosis score and urolithiasis among non-alcoholic fatty liver disease (NAFLD) patients in China: a cross-sectional study

BMJ Open, 2019
Objective Mounting data now support a strong link between the presence of non-alcoholic fatty liver disease (NAFLD) and an increased risk of urolithiasis.
Xu Wang, Yan Xu, Shaoyou Qin, Jiangbin Wang, Changyu Zhou, Yonggui Zhang, Song Wang   +6 more
doaj   +1 more source

Urine diagnostics in paediatric intestinal failure: A prospective cohort study of alternative sampling methods

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Regular monitoring of urinary electrolyte excretion and kidney function is essential in children with intestinal failure (IF) receiving long‐term parenteral nutrition (PN). This study evaluated alternative urine sampling methods against 24‐h urine collection (UC) and assessed the prevalence of chronic kidney disease (CKD) and renal ...
Anna Sakaeva, Andreas Busch, Johannes Holle, Hendrik Bartolomaeus, Bernd Fode, Ilias Tsiflikas, Ekkehard Sturm, Christoph Slavetinsky, Simon Scherer, Jörg Fuchs, Justus Lieber, Steven W. Warmann, Johannes Hilberath   +12 more
wiley   +1 more source

An Evaluation of Nutritional Factors on The Prevalence of Urolithiasis in Cats at The Veterinary Teaching Hospital, Universitas Airlangga During 2017-2019

Jurnal Medik Veteriner, 2023
Stones, or uroliths, in the urinary tract cause a disorder called urolithiasis. Patients with urolithiasis may experience blockage and possibly mortality; therefore, prompt treatment is imperative.
Daffa Amanul Mahdi, I Komang Wiarsa Sardjana, Ira Sari Yudaniayanti, Agnes Theresia Soelih Estoepangestie, Nusdianto Triakoso, Hardany Primarizky   +5 more
doaj   +1 more source

Save the Bladder: Continent Urinary Diversion as Best Practice for Patients With Refractory Neurogenic Lower Urinary Tract Dysfunction

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Refractory neurogenic lower urinary tract dysfunction presents an obstinate clinical problem. For patients who fail nonsurgical measures, we advocate for bladder‐sparing, continent urinary diversion as the optimal approach to management.
Brian W. Chao, Sean P. Elliott
wiley   +1 more source

Urolithiasis: Prevalence, risk factors, and public awareness regarding dietary and lifestyle habits in Jeddah, Saudi Arabia in 2017

Urology Annals, 2020
Introduction: Urolithiasis is a public health concern, yet there are limited studies in our community. This study aimed to provide a current estimate of the prevalence of urolithiasis and to evaluate the public's awareness about dietary and lifestyle ...
Nada Yasser Baatiah, Raghad Bader Alhazmi, Fatmah Ali Albathi, Esraa Ghazi Albogami, Abdullah Khalid Mohammedkhalil, Basim Saleh Alsaywid   +5 more
doaj   +1 more source