Results 11 to 20 of about 28,484 (289)
Disulfidptosis is a newly discovered mode of cell death induced by disulfide stress. However, the prognostic value of disulfidptosis-related genes (DRGs) in renal cell carcinoma (RCC) remains to be further elucidated.
Kai Xu+16 more
doaj +1 more source
DOT1L Epigenetically Regulates Autophagy and Mitochondria Fusion in Cell Lines of Renal Cancer
Objectives DOT1L, a histone methylase, is overexpression in renal cell cancer. However, the role and detailed molecular mechanism of DOT1L involved in renal cancer development remain unknown.
Yanguang Hou MD+5 more
doaj +1 more source
Chondroitin sulfate (CS) is one of the most abundant glycosaminoglycans in prostate cancers. Here the authors show that inhibition of the androgen receptor pathway leads to the upregulation of CS, which promotes prostate cancer growth and metastasis.
Nader Al-Nakouzi+25 more
doaj +1 more source
Publication of original research in urologic journals--a neglected orphan? [PDF]
The pathophysiologic mechanisms behind urologic disease are increasingly being elucidated. The object of this investigation was to evaluate the publication policies of urologic journals during a period of progressively better understanding and management
Jens Mani+6 more
doaj +1 more source
Internalization and trafficking of CSPG-bound recombinant VAR2CSA lectins in cancer cells
Proteoglycans are proteins that are modified with glycosaminoglycan chains. Chondroitin sulfate proteoglycans (CSPGs) are currently being exploited as targets for drug-delivery in various cancer indications, however basic knowledge on how CSPGs are ...
Chris Kedong Wang+16 more
doaj +1 more source
Trends in urological stone disease [PDF]
Study Type – Therapy (case series)Level of Evidence 4What's known on the subject? and What does the study add? Urolithiasis is a major clinical and economic burden for health care systems. International epidemiological data suggest that the incidence and prevalence of stone disease is increasing. This study demonstrates that the number of diagnoses and
Turney, B+3 more
openaire +4 more sources
Urologic emergencies in a low-resource setting: A 10-year review from South-Western Nigeria
Background: Emergency presentations are quite an important aspect of the urologic practice, and prompt attention is necessary to relieve symptoms, limit morbidity, and prevent mortality.
A A Salako+7 more
doaj +1 more source
One year after the prevalence of the novel coronavirus pandemic, some aspects of the physiopathology, treatment and progression of coronavirus 2019 disease (COVID-19) have remained unknown.
Mojtaba Shafiekhani+6 more
doaj +1 more source
Urobiome: An outlook on the metagenome of urological diseases [PDF]
The urinary tract likely plays a role in the development of various urinary diseases due to the recently recognized notion that urine is not sterile. In this mini review, we summarize the current literature regarding the urinary microbiome and mycobiome and its relationship to various urinary diseases.
Rachel Shoemaker, Jayoung Kim
openaire +3 more sources
Clinical implications of underactive bladder [PDF]
Underactive bladder (UAB) is a common urologic condition but a complex disease that causes troublesome lower urinary tract symptoms. Currently, management of UAB remains unsatisfactory. Also, many urological diseases can be combined with UAB.
Kwang Jin Ko, Chung Un Lee, Kyu-Sung Lee
doaj +1 more source