Results 31 to 40 of about 28,484 (289)

Hematúria.

Acta Médica Portuguesa, 1999
Patients referred for hematuria work-up are frequently seen in the urologic practice. The initial evaluation does not require the participation of a urologist or nephrologist, due to the false sense of security in the evaluation of an asymptomatic and ...
A Milheiro, R Prisco
doaj   +1 more source

Recent Advances in Stimuli‐Responsive Materials and Soft Robotic Actuators for Bioelectronic Medicine

Advanced Materials, EarlyView.
This review explores the integration of responsive materials and soft robotic actuators with implantable electronics to address key challenges in bioelectronic medicine. By enabling shape actuation, these technologies improve deployment, adaptability, and accuracy in minimally invasive procedures.
Chaoqun Dong, George G. Malliaras
wiley   +1 more source

Engineering CRISPR System‐Based Bacterial Outer Membrane Vesicle Potentiates T Cell Immunity for Enhanced Cancer Immunotherapy

Advanced Materials, EarlyView.
This study develops a multifunctional CRISPR‐dCas9‐based OMV platform termed OMV‐C9I12, which facilitates the coexpression of CXCL9 and IL‐12 within tumor cells. This platform enhances T cell recruitment and activation, synergizes with anti‐PD‐1/PD‐L1 immunotherapy, and amplifies antitumor T cell immunity.
Hongjin Wang, Hengji Zhan, Bolin Pan, Leli Zeng, Zehua Chen, Sen Liu, Qiang Zhang, Xuwei Hong, Junlin Lu, Xinrou Lin, Xiao Zhao, Jiajian Lai, Kaiwen Jie, Ye Li, Jianmei Zhong, Shengmeng Peng, Siting Chen, Changhao Chen, Wenlong Zhong, Shaoxu Wu, Yihang Pan, Tianxin Lin, Xu Chen   +22 more
wiley   +1 more source

Prevalence and trends of selected urologic conditions for VA healthcare users

BMC Urology, 2006
Background Conducted as part of the Urologic Diseases in America project whose aim was to quantify the burden of urologic diseases on the American public, this study focuses on Veterans Health Administration (VHA) users as a special population to ...
Fischer Michael J, Taylor Brent C, Zhang Huiyuan, Sohn Min-Woong, Yano Elizabeth M, Saigal Christopher, Wilt Timothy J   +6 more
doaj   +1 more source

Changing patterns of urologic emergency visits and admissions during the COVID-19 pandemic: a retrospective, multicenter, nationwide study

Archives of Medical Science, 2020
Introduction We aimed to examine the change in the number and severity of visits to the emergency departments (EDs) and subsequent admissions for urgent urologic conditions in the early stage of the coronavirus disease 2019 (COVID-19) pandemic in Poland.
Pawel Rajwa, Mikolaj Przydacz, Wojciech Krajewski, Blazej Kuffel, Piotr Zapala, Aleksandra Krzywon, Alexander J. Cortez, Bartosz Dybowski, Remigiusz Stamirowski, Marcin Jarzemski, Rafal B. Drobot, Pawel Stelmach, Krystyna Mlynarek, Mateusz Marcinek, Maciej Przudzik, Wiktor Krawczyk, Jakub Ryszawy, Dominik Choragwicki, Lukasz Zapala, Marcin Lipa, Michal Pozniak, Dawid Janczak, Szymon Słomian, Jan Łaszkiewicz, Marcel Nowak, Marcin Miszczyk, Marek Roslan, Michał Tkocz, Romuald Zdrojowy, Andrzej Potyka, Tomasz Szydełko, Tomasz Drewa, Piotr Jarzemski, Piotr Radziszewski, Marcin Slojewski, Artur Antoniewicz, Andrzej Paradysz, Piotr L. Chlosta   +37 more
doaj   +1 more source

Single‐Cell Analysis Reveals that Vitamin C Inhibits Bone Metastasis of Renal Cancer via Cell Cycle Arrest and Microenvironment Remodeling

Advanced Science, EarlyView.
3D‐cultured renal cancer cells exhibit stem‐like phenotypes and are more efficient in generating bone metastases. Vitamin C treatment can suppress the development of bone metastasis. Single‐cell transcriptomic analysis reveals that vitamin C inhibits metastasis by inducing tumor cell cycle arrest, suppressing osteoclast differentiation, and reducing ...
Jianye Zhang, Qi Zhang, Gang Lin, Ying Wang, Juan Li, Ping Wang, Jie Qi, Yuan Liang, Shiming He, Yanqing Gong, Ninghan Feng, Yang Wang, Yuanyuan Ma, Mei Zhang, Yue Shi, Xuesong Li, Weimin Ci, Liqun Zhou   +17 more
wiley   +1 more source

Management of the urological tract in children with anorectal malformations – a contemporary review

Therapeutic Advances in Urology, 2023
Anorectal malformations (ARMs) consist of a broad spectrum of congenital anomalies that are associated with an equally wide variety of urological abnormalities, often with increasing incidence as the severity of the ARM increases.
Kelly T. Harris, Duncan T. Wilcox
doaj   +1 more source

Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset

Advanced Science, EarlyView.
This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu, Zhengyuan Zhou, Sascha Schäuble, Wolfgang Vivas, Karen Dlubatz, Michael Bauer, Sebastian Weis, Mervyn Singer, Roman Lukaszewski, Gianni Panagiotou   +9 more
wiley   +1 more source

The E3 Ligase NEDD4L Prevents Colorectal Cancer Liver Metastasis via Degradation of PRMT5 to Inhibit the AKT/mTOR Signaling Pathway

Advanced Science, EarlyView.
Neural precursor cell expressed developmentally down‐regulated gene 4‐like (NEDD4L) prevents colorectal cancer liver metastasis through ubiquitination and degradation of protein arginine methyltransferase 5 (PRMT5). PRMT5 degradation attenuates the methylarginine of AKT1.
Zhewen Dong, Xiaofei She, Junxian Ma, Qian Chen, Yaqun Gao, Ruiyan Chen, Huanlong Qin, Bing Shen, Hua Gao   +8 more
wiley   +1 more source

Cutaneous metastasis: An unusual presenting feature of urologic malignancies

Urology Annals, 2016
Urological malignancies are well known for their ability to metastasize widely. The incidence of cutaneous metastasis from all urologic malignancies has been reported to be 0.73–1.3% with the primary most commonly being renal cell carcinoma followed by ...
Arun Ramdas Menon, Anju Sussanna Thomas, Nivedita Suresh, Shashank Malagi Shashidhar   +3 more
doaj   +1 more source