Results 1 to 10 of about 14,643 (342)

CAR-T Cells in the Treatment of Urologic Neoplasms: Present and Future [PDF]

Frontiers in Oncology, 2022
In recent years, with the breakthrough of CAR-T cells in the treatment of hematological tumors, they are increasingly being used to treat solid tumors, including urologic neoplasms.
Zhengchao Zhang, Zhengchao Zhang, Dong Li, Heng Yun, Wei Liu, Keqiang Chai, Jie Tong, Tongwei Zeng, Zhenghua Gao, Yongqiang Xie   +9 more
doaj   +6 more sources

Targeting c-Met in the treatment of urologic neoplasms: Current status and challenges [PDF]

Frontiers in Oncology, 2023
At present, studies have found that c-Met is mainly involved in epithelial-mesenchymal transition (EMT) of tumor tissues in urologic neoplasms. Hepatocyte growth factor (HGF) combined with c-Met promotes the mitosis of tumor cells, and then induces ...
Pengxiao Su, Ming Zhang, Xin Kang
doaj   +6 more sources

Microbiome in urologic neoplasms: focusing on tumor immunity [PDF]

Frontiers in Immunology
Urological tumors are an important disease affecting global human health, and their pathogenesis and treatment have been the focus of medical research.
Jun Zou, Baisheng Xu, Hongbing Gao, Peiyue Luo, Tao Chen, Huanglin Duan   +5 more
doaj   +5 more sources

Impact of Diagnosis of Urologic Cancer on Male Sexuality and Patients’ Perceptions of Health Professional's Approach [PDF]

International Brazilian Journal of Urology
Objective: To evaluate the impact of a urological neoplasm diagnosis on male sexuality and examine patient perceptions of healthcare professionals’ engagement with sexuality at diagnosis.
Rodrigo Barros, Angelo Maurílio Fosse Jr, Alex Schul, Gabriel Mangas, Caio Henrique da Silva Teixeira, Tiago Ninis, João Paulo Martins Carvalho, Luciano A. Favorito   +7 more
doaj   +2 more sources

Urinary microbiome profile in men with genitourinary malignancies [PDF]

Investigative and Clinical Urology, 2022
Purpose: Recent advances in molecular biology technology have allowed identification of microbial communities in the urinary tract, and urinary microbiome is associated with various urological diseases. In this study, we aimed to characterize the urinary
Hyun Kyu Ahn, Kwangmin Kim, Junhyung Park, Kwang Hyun Kim   +3 more
doaj   +1 more source

Epidemiology of Urologic Cancer in Korea: Nationwide Trends in the Last 2 Decades [PDF]

Journal of Urologic Oncology, 2023
Purpose This study assessed recent trends in the incidence of urologic cancer and patient survival in Korea. Materials and Methods The incidence of urologic cancer in Korea was calculated based on the Korea National Cancer Incidence Database and the ...
Sang Heon Han, Hyeong Dong Yuk
doaj   +1 more source

The Utility of Nicotinamide N-Methyltransferase as a Potential Biomarker to Predict the Oncological Outcomes for Urological Cancers: An Update

Biomolecules, 2021
Nicotinamide N-methyltransferase (NNMT) catalyzes the N-methylation reaction of nicotinamide, using S-adenosyl-L-methionine as the methyl donor. Enzyme overexpression has been described in many non-neoplastic diseases, as well as in a wide range of solid
Roberto Campagna, Valentina Pozzi, Graziana Spinelli, Davide Sartini, Giulio Milanese, Andrea Benedetto Galosi, Monica Emanuelli   +6 more
doaj   +1 more source

Changes in male sexuality after urologic cancer: a narrative review

International Brazilian Journal of Urology, 2023
Objective To describe the most common sexual problems and changes experienced by male urological cancer survivors, focusing on evidence-based practices for assessment and intervention.
Rodrigo Barros, Luciano A. Favorito, Bruno Nahar, Ricardo Almeida Jr, Ranjith Ramasamy   +4 more
doaj   +1 more source

Carcinomas in the bladder with papillary and pseudopapillary morphology - not always urothelial

Surgical and Experimental Pathology, 2020
Background Urothelial carcinoma shows wide plasticity and broad morphologic spectrum. In many instances, the presence of papillary morphology is reassuring of the urothelial histogenesis of a high-grade invasive lesion but is not pathognomonic.
Daniel Abensur Athanazio, Maiara Ferreira de Souza, Maria Estela Pompeu do Amaral   +2 more
doaj   +1 more source

Calcitriol-mediated hypercalcemia as an immune-related adverse event in a patient receiving nivolumab and ipilimumab for metastatic renal cell carcinoma, case report

BMC Urology, 2021
Background Severe hypercalcemia is often associated with uncontrolled malignancy through several mechanisms. However, calcitriol-mediated hypercalcemia is a rare etiology for advanced solid tumors.
Kai Johnson, Majd Issa, Anish Parikh, Paul Monk, Ming Yin, Amir Mortazavi, Yuanquan Yang   +6 more
doaj   +1 more source