CAR-T Cells in the Treatment of Urologic Neoplasms: Present and Future [PDF]
In recent years, with the breakthrough of CAR-T cells in the treatment of hematological tumors, they are increasingly being used to treat solid tumors, including urologic neoplasms.
Zhengchao Zhang +9 more
doaj +4 more sources
Microbiome in urologic neoplasms: focusing on tumor immunity [PDF]
Urological tumors are an important disease affecting global human health, and their pathogenesis and treatment have been the focus of medical research.
Jun Zou +5 more
doaj +4 more sources
Targeting c-Met in the treatment of urologic neoplasms: Current status and challenges [PDF]
At present, studies have found that c-Met is mainly involved in epithelial-mesenchymal transition (EMT) of tumor tissues in urologic neoplasms. Hepatocyte growth factor (HGF) combined with c-Met promotes the mitosis of tumor cells, and then induces ...
Pengxiao Su, Ming Zhang, Xin Kang
doaj +2 more sources
Global, regional, and National burden of urologic neoplasms from 1990 to 2021 and future projections to 2050, a comprehensive analysis for global burden of disease [PDF]
Background Urologic neoplasms are considered to pose a serious threat to patients’ lives and quality of life. Analyzing and describing the global disease burden of urologic neoplasms is necessary.
Zhao Yang +4 more
doaj +2 more sources
Case report of seminal vesicle schwannoma with synchronous prostate cancer [PDF]
Seminal vesicle schwannomas are rare entities, reported in only a handful of cases since 2002. These benign neoplasms originate from the peripheral nerve sheath and are typically found incidentally on imaging or during the workup of nonspecific urologic ...
Mitali Kini +10 more
doaj +2 more sources
Urinary microbiome profile in men with genitourinary malignancies [PDF]
Purpose: Recent advances in molecular biology technology have allowed identification of microbial communities in the urinary tract, and urinary microbiome is associated with various urological diseases. In this study, we aimed to characterize the urinary
Hyun Kyu Ahn +3 more
doaj +1 more source
Epidemiology of Urologic Cancer in Korea: Nationwide Trends in the Last 2 Decades [PDF]
Purpose This study assessed recent trends in the incidence of urologic cancer and patient survival in Korea. Materials and Methods The incidence of urologic cancer in Korea was calculated based on the Korea National Cancer Incidence Database and the ...
Sang Heon Han, Hyeong Dong Yuk
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Updates in Histologic Grading of Urologic Neoplasms [PDF]
Context.—Tumor histology offers a composite view of the genetic, epigenetic, proteomic, and microenvironmental determinants of tumor biology. As a marker of tumor histology, histologic grading has persisted as a highly relevant factor in risk stratification and management of urologic neoplasms (ie, renal cell carcinoma, prostatic adenocarcinoma, and ...
Travis, Rice-Stitt +3 more
openaire +2 more sources
Management of bladder tumors in pregnancy: A case of tumor prolapse and avulsion during labor
Pregnancy presents unique obstacles to diagnosis and management of urologic disease. We present a case of a primigravid female with clot retention requiring evacuation in the operating room due to the avulsion of a bladder mass which prolapsed during ...
Kate A. Hanson +5 more
doaj +1 more source
Nicotinamide N-methyltransferase (NNMT) catalyzes the N-methylation reaction of nicotinamide, using S-adenosyl-L-methionine as the methyl donor. Enzyme overexpression has been described in many non-neoplastic diseases, as well as in a wide range of solid
Roberto Campagna +6 more
doaj +1 more source

