Results 41 to 50 of about 9,546 (199)

KMT5C‐Mediated H4K20me3 Recruits EWSR1 to Propel Clear Cell Renal Cell Carcinoma Progression via Regulating ACADM Transcription and m6A Modification

Med Research, EarlyView.
A schematic diagram illustrating the KMT5C‐H4K20me3‐EWSR1‐ACADM signaling axis and its role in ccRCC progression. Key Outcomes: KMT5C/H4K20me3 are upregulated in ccRCC and predict poor prognosis. EWSR1 is a novel noncanonical H4K20me3 reader in ccRCC. KMT5C/EWSR1 co‐repress ACADM via transcription and m6A modification. A‐196 + sunitinib synergistically
Chengjian Ji, Da Zhong, Tian Rao, Xiaojun Li, Weiyu Kong, Xi Zhang, Xiyi Wei, Bing Yao, Xinqiang Li, Ninghong Song, Chao Qin   +10 more
wiley   +1 more source

Impact of COVID‐19 and Vaccination on Lower Urinary Tract Symptoms: Insights From a Prospective Cohort Study

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims To evaluate the prevalence, clinical course, and risk factors of lower urinary tract symptoms (LUTS) in patients hospitalized with COVID‐19, and to assess associations with comorbidities, disease severity, and vaccination status. Methods We conducted a prospective cohort study of adult patients hospitalized with confirmed COVID‐19, who ...
Julia Duarte de Souza, Jose de Bessa Jr., Natássia Cristina Carboni Truzzi, Carolina Trigo Rocha, Bruno Camargo Rocha Paim de Araujo, Julyana Kanate Mazzoni Moromizato, Thulio Bosi Vieira Brandão, Rachel Mazoni Costa, Marcelo Hisano, Zein Mohamed Sammour, Homero Bruschini, William Carlos Nahas, Cristiano Mendes Gomes   +12 more
wiley   +1 more source

Preventing rare contralateral ureteral injury during robotic-assisted nephroureterectomy: lessons from a surgical complication

BMC Urology
Robotic-assisted laparoscopic nephroureterectomy (RALN) is a common approach for upper tract urothelial carcinoma (UTUC), offering advantages such as reduced morbidity and improved recovery.
Yen Ho, Chung-Howe Lai, Kuan-Ting Lin, Ke-Hsun Lin, Syuan-Hao Syu   +4 more
doaj   +1 more source

Unusual iatrogenic common femoral artery injury during penile prosthesis placement in gender-confirming surgery

Annals of Vascular Surgery - Brief Reports and Innovations
Introduction: Gender dysphoria refers to the distress or discomfort experienced when a person's gender identity does not align with the sex assigned at birth.
Elena Giacomelli, Marianna Peruffo, Andrea Cocci, Marta Pezzoli, Raffaele Pulli, Walter Dorigo   +5 more
doaj   +1 more source

Fascial Mild Urethral Sling or Artificial Urinary Sphincter in the Neurological Women Population, a Multicenter Study

Neurourology and Urodynamics, EarlyView.
ABSTRACT Background Achieving continence in patients with neurogenic bladder is a difficult goal especially when stress urinary incontinence (SUI) due to intrinsic sphincter deficiency is involved. Two techniques are commonly used in that setting, but they have never been directly compared: the artificial urinary sphincter (AUS) and the fascial ...
Alicia Blondeau, Charles Mazeaud, Rose Khavari, Melody Ong, Alexandre Dubois, Alice Pitout, Pierre Lecoanet, Benoit Peyronnet   +7 more
wiley   +1 more source

One‐Year Transcutaneous Tibial Nerve Stimulation Treatment Persistence in Lower Urinary Tract Dysfunction: Clinical and Urodynamic Associated Factors in a Prospective Observational Study

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims To assess 1‐year Transcutaneous Tibial Nerve Stimulation (TTNS) treatment persistence in routine clinical care and to explore clinical and urodynamic factors associated with treatment persistence in patients with lower urinary tract dysfunction (LUTD).
Damien Prat, Evelyne Castel‐Lacanal, Thibaut Brierre, Gaetane Foures, Camille Cormier, Xavier De Boissezon, David Gasq, Philippe Marque, Xavier Gamé, Emmeline Montané   +9 more
wiley   +1 more source

New and Emerging Artificial Urinary Sphincters for Male Stress Urinary Incontinence: From Gold Standard to Next Generation

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction For more than four decades, the AMS‐800 has remained the clinical benchmark device for the treatment of male stress urinary incontinence (SUI). Although it remains the gold standard for male SUI, the AMS‐800 has continued to have limitations such as suboptimal post‐operative continence rates, fixed hydraulic pressure, need for ...
Erin C. Schnell, Connie N. Wang, Eric S. Rovner   +2 more
wiley   +1 more source

The Benefits of Adding Non‐Antimuscarinic Pharmaceuticals in Combination With Beta‐3 Agonists for Overactive Bladder Treatment: A Systematic Review

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Antimuscarinics, as the current first‐line pharmacologic therapies for overactive bladder, exhibit low patient adherence and high rates of reported side effects. As a modern alternative pharmaceutical treatment, beta‐3 agonists, which relax the urinary bladder, may be more tolerable for patients, increasing adherence and ...
Felicity Smith, Charlotte Phelps, Christian Moro   +2 more
wiley   +1 more source

Evolving Sacrocolpopexy Technique Trends

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Sacrocolpopexy (SCP) is widely considered the gold standard procedure for repairing apical and multi‐compartment prolapse. Despite its long‐standing and widespread use, significant technical variations persist, yet these differences have not been well‐characterized or linked to surgical outcomes.
Christina Sze, Carolina Martinez Fernandez, Gabriel Andino, Maali LaFrance Frater, Stephanie Sansone, Sonia Bhandari Randhawa, Gary E. Lemack, Ramy Goueli, Maude Carmel   +8 more
wiley   +1 more source

Development and Validation of Urodynamic Report Writer: A Chat GPT App

Neurourology and Urodynamics, EarlyView.
ABSTRACT Objective Accurate interpretation and reporting of urodynamic studies are essential for diagnosis and management of lower urinary tract dysfunction, yet remain time‐consuming and operator‐dependent. To develop and validate the Urodynamic Report Writer App (URapp), a GPT‐4o‐based virtual assistant that supports interpretation of clinician ...
Riccardo Lombardo, Carolina Cerullo, Marta Santioni, Emanuele Pillitteri, Claudia Lorenti, Sabrina De Cillis, Cristian Fiori, Giorgia Tema, Antonio Franco, Beatrice Turchi, Matteo Romagnoli, Antonio Nacchia, Antonio Cicione, Antonio Pastore, Andrea Fuschi, Andrea Tubaro, Cosimo De Nunzio   +16 more
wiley   +1 more source