Results 81 to 90 of about 9,546 (199)

Symptom‐guided reduction of BCG dwell time: findings from the north‐REG randomized trial

BJU International, EarlyView.
Objectives To evaluate the impact of personalized dwell‐time (DT) reductions on symptom prevalence and systemic toxicities in patients undergoing Bacillus Calmette–Guérin (BCG) instillation for non‐muscle invasive bladder cancer (NMIBC). Methods Within a multinational randomized controlled trial (North‐REG Dwell Time Study [NCT04701151]), 225 patients ...
Lene Munk, Josephine Maria Hyldgaard, Vanaja Kumasegaram, Rikke Vilsbøl Milling, Simone Buchardt Brandt, Juan Luis Vásquez, Knud Fabrin, Gitte Wrist Lam, Lasse Bro, Sigurður Gudjonsson, Viveka Ströck, Tomas Jerlsström, Tomas Thiel, Maria Skydt Lindgren, Jørgen Bjerggaard Jensen, Charlotte Graugaard‐Jensen   +15 more
wiley   +1 more source

Bladder washing cytology in the initial evaluation of patients with neuro‐urological disorders: to do or not to do?

BJU International, EarlyView.
Objectives To evaluate if bladder washing cytology (BWC) provides a diagnostic benefit in the initial evaluation of patients with neuro‐urological disorders. Patients and Methods This prospective cross‐sectional study investigated a consecutive series of patients with lower urinary tract symptoms referred for neuro‐urological evaluation at our ...
Fabienne Lehner, Sarah Dugas, Veronika Birkhäuser, Oliver Gross, Lorenz Leitner, Ulrich Mehnert, Lara Stächele, Collene E. Anderson, Thomas M. Kessler   +8 more
wiley   +1 more source

Diet and risk of bladder cancer: a systematic review of epidemiological evidence

BJU International, EarlyView.
Purpose Although tobacco use and occupational exposures are established risk factors for urothelial cancer (UC), the influence of dietary factors remains uncertain. We conducted a systematic review to synthesize evidence from prospective cohort studies examining associations between dietary exposures and UC incidence. Methods A comprehensive literature
Keiichiro Miyajima, Marcin Miszczyk, Navid Roessler, Shota Inoue, Paweł Rajwa, Akihiro Matsukawa, Fumihiko Urabe, Keiichiro Mori, Takafumi Yanagisawa, Pierre I. Karakiewicz, Jeremy Yuen‐Chun Teoh, Alberto Briganti, Lin Yang, Eva Schernhammer, Takahiro Kimura, Shahrokh F. Shariat   +15 more
wiley   +1 more source

NRF2/xCT‐Mediated Antioxidant Adaptation Attenuates Apoptosis Induced by ASCT2 Inhibition in Prostate Cancer

Cancer Science, EarlyView.
ASCT2 inhibition induces ROS accumulation and activates NRF2‐dependent xCT upregulation in prostate cancer. This adaptive response partially supports residual cystine acquisition and glutathione synthesis, whereas combined ASCT2 and xCT inhibition disrupts redox compensation and predominantly promotes apoptotic cell death.
Jiaxing Wei, Yasutaka Yamada, Takaaki Tamura, Masahiro Sugiura, Xue Zhao, Meng Ni, Adilan Aierken, Tomokazu Sazuka, Yusuke Imamura, Shinichi Sakamoto   +9 more
wiley   +1 more source

Triggering SORL1 Expression Restricts ccRCC Progression by Inducing Ubiquitination‐Mediated c‐Myc Degradation

Cancer Science, EarlyView.
Targeted triggering of SORL1 expression through a novel MPOC delivery system could inhibit ccRCC progression through binding to TRIM22 and further promoting ubiquitination‐mediated C‐MYC degradation, thereby facilitating the inhibition of oxidative phosphorylation through transcriptional repression of ACO2 and IDH2.
Keyi Wang, Wei Song, Qi Bai, Shaoze Shen, Xiao Lu, Chenxuan Su, Shi Yang, Yidi Wang, Yu Xia, Rui Zan, Shuai Jiang, Jianming Guo   +11 more
wiley   +1 more source

Impact of surgical start time on clinical outcomes in urologic surgery: a single-center study of major oncologic surgeries and adrenalectomy. [PDF]

World J Urol
Kobatake K, Goto K, Kohada Y, Naito M, Miyamoto S, Sekino Y, Kitano H, Hieda K, Hinata N.   +8 more
europepmc   +1 more source

Hybrid grading systems improve progression risk stratification in non‐invasive papillary urothelial carcinoma and support a histomorphological continuum of disease progression

Histopathology, EarlyView.
Hybrid grading systems significantly improve progression‐risk stratification in non‐invasive papillary urothelial carcinoma compared with the WHO 2004/2016 binary classification, with most benefit achieved by a Hybrid 3‐Tier framework. These findings support the existence of a histomorphological continuum of progression risk within the conventional ...
Jane K Nguyen, Marcello P Toscano, Jianbo Li, Sean R Williamson, Christopher G Przybycin, Chia‐Sui Kao, Jonathan L Myles, Kristýna Pivovarčíková, Marián Švajdler, Marek Brousil, Mohamed Eltemamy, Laura Bukavina, Venkatesh Krishnamurthi, Christopher Weight, Rebecca A Campbell, Nima Almassi, Reza Alaghehbandan   +16 more
wiley   +1 more source

Patient perspectives on single-port versus multi-port robotic-assisted urologic oncology procedures: a survey-based analysis. [PDF]

J Robot Surg
Nalluri R, Khanna K, Chamkeri R, Patel T.   +3 more
europepmc   +1 more source

Patient and Carer Participation in Reporting Patient Safety Incidents During Hospital Admission: A Scoping Review

Journal of Advanced Nursing, EarlyView.
ABSTRACT Background More than one in 10 patients experience harm in hospital, and patients with communication support needs are at higher risk. Patients and their carers are well‐placed to provide insights into patient safety incidents that may result in harm, which is essential to improving patient safety in hospitals.
Rebecca Sullivan, Tanya Ramadan, Shu En Lee, Robyn O'Halloran   +3 more
wiley   +1 more source

Paediatric regional anaesthesia and peripheral nerve blocks in paediatric outpatient surgery. Prospective, single-center, pragmatic comparative cohort study. [PDF]

Pediatr Surg Int
Perez D, Jaber G, Neeman BB, Raisin G, Zeldin A, Armon Y, Feldman E, Gozal Y, Ostrovsky IA, Chertin B.   +9 more
europepmc   +1 more source