Results 41 to 50 of about 24,622 (310)

FASLG Derived from Fibroblasts in Hydroxyapatite‐Rich Microenvironment Induces Urothelial Anoikis to Trigger Randall's Plaque Exposure

Advanced Science, EarlyView.
Randall's plaques (RP) serve as the nidus for calcium oxalate (CaOx) kidney stones. The current study reveals that hydroxyapatite (HAP) crystals activate the THY1–GSK3α/β–β‐catenin axis in renal interstitial fibroblasts (hRIFs), inducing FASLG secretion.
Minghui Liu, Maolan Wu, Meng Gao, Yongchao Li, Miao Yuan, Zhangcheng Liao, Zhi Liu, Yizhou Wang, Yu Cui, Jinbo Chen, Cheng He, Zhiyong Chen, Feng Zeng, Hequn Chen, Zewu Zhu   +14 more
wiley   +1 more source

Can a graft be placed over a flap in complex hypospadias surgery? An experimental study in rabbits

International Brazilian Journal of Urology
Purpose: To develop a rabbit experimental study to test the hypothesis that surgical repair of hypospadias with severe ventral curvatures might be completed in one stage, if a graft, such as buccal mucosa, could be placed over the tunica vaginalis flap ...
Ricardo Marcondes de Mattos, Sérgio R.R. de Araújo, Juliany Gomes Quitzan, Bruno Leslie, Herick Bacelar, João Luiz Gomes Parizi, Gustavo Marconi Caetano Martins, Marcela Leal da Cruz, Antonio Macedo Jr.   +8 more
doaj   +1 more source

Penile fracture: A rare case of simultaneous rupture of the one corpus cavernosum and complete urethral rupture [PDF]

Vojnosanitetski Pregled, 2015
Introduction. Penile fracture is a traumatic rupture of tunica albuginea and the tumescent corpora cavernosa due to the nonphysiological bending of the penile shaft, presenting with or without rupture of corpus spongiosum and urethra.
Nale Đorđe, Bojanić Nebojša, Nikić Predrag   +2 more
doaj   +1 more source

Ex vivo renal perfusion and autotransplantation in treatment of calculous disease or abdominal aortic aneurysm. [PDF]

, 1975
Two more indications are described for temporary ex vivo perfusion of kidneys with revascularization of these organs as autografts to orthotopic or heterotopic locations. One of the patients had staghorn calculi which were removed from a solitary kidney.
Belzer, Belzer, Charles G. Halgrimson, Charles W. Putnam, Corman, Creech, Dale Atkins, Debakey, Derek P. Stables, Gauke Kootstra, Guerriero, Harrison, Mehmet Haberal, Orcutt, Robert W. Beart, Ronald Pfister, Starzl, Thomas E. Starzl   +17 more
core   +1 more source

Dynamic Shifts in ER–Plasma Membrane Junctions Signaling Define Pro‐Metastatic N‐Glycosylation and Predict Prostate Cancer Progression

Advanced Science, EarlyView.
Prostate cancer remains a leading cause of male cancer death, yet screening cannot reliably identify aggressive disease, underscoring the need for tissue biomarkers. It is shown that primary tumors increase ER–plasma membrane junction signaling via STIM1/ORP5, whereas metastasis features their loss, Golgi dispersal, and rapid conversion of high‐mannose
Amanda J. Macke, Tania Kamal, Taylor E. Divita, Artem N. Pachikov, Chad A. LaGrange, Rajesh Ravichandran, Martha Morton, Robert Powers, Haowen Qiu, Jean‐Jack M. Riethoven, Colm Morrissey, Melinda Wojtkiewicz, Rebekah L. Gundry, Carol A. Casey, Armen Petrosyan   +14 more
wiley   +1 more source

Bioorthogonal Fluorogenic Reporters for Noninvasive Imaging and Urinalysis of Immunotherapeutic Response in Renal Cell Carcinoma

Advanced Science, EarlyView.
This study reported renal‐clearable bio‐orthogonal near‐infrared fluorogenic probes (BGRs) that specifically imaging and urinalysis of granzyme B for dynamic evaluation of RCC immunotherapy. BGRs not only differentiate immunotherapeutic responses in orthotopic RCC mice, but also enable sensitive optical urinalysis of granzyme B in clinical specimens ...
Xingyue Yang, Baoshuai Liang, Liangmin Fu, Weiliang Deng, Yuyan Jiang, Weiping Xu, Jinwei Chen, Ya Zhou, Ke Wu, Jiaguo Huang   +9 more
wiley   +1 more source

Is the use of ultra-low insufflation pressure safe and feasible in robot assisted radical prostatectomy

Urology Research and Practice, 2021
Objective: Current innovations in minimally invasive surgery include using ultra-low insufflation pressure with the aim of improving peri-operative and short-term clinical outcomes.
Christopher Johnstone, Jack Hammond, Vishwanath Hanchanale   +2 more
doaj   +1 more source

Large‐Scale Quantitative Morphometry of Platelet α‐Granules via SIM Super‐Resolution Microscopy for Cancer Liquid Biopsy

Advanced Science, EarlyView.
ABSTRACT Blood‐based liquid biopsies hold transformative potential for non‐invasive cancer management, but current approaches relying on rare circulating tumor components limit their broad clinical utility. Platelets, abundant in blood and mediating diverse cancer‐associated responses, represent a compelling yet largely unexplored alternative.
Yan Ma, Huan Deng, Zelin Liu, Simei Zhong, Liangliang Wang, Mu He, Ning Jing, Lihua Dai, Yuzhen Basang, Xiao‐Yu Hu, Changyi Zhang, Huimin Zeng, Haoren Shao, Zhe Yang, Shanshan Zhao, Xiaohai Hu, Chuanjie Zhang, Xiaowei Wu, Jing Xu, Shaoqun Zeng, Jing Yuan, Qiang Li, Ziwei Qu, Zhenya Hong, Lingjuan Chen, Hanhua Dong, Jia Guo, Zhiqiang Han, Yu‐Hui Zhang   +28 more
wiley   +1 more source

Prevalence of frailty syndrome in urological patients undergoing major elective surgical procedure due to malignancy

Central European Journal of Urology, 2022
The group of elderly urological patients is growing. A majority of urological operations is performed in this group. The current model of preoperative assessment is developed to be effective in younger groups of patients but not in the elderly. Frailty syndrome has been confirmed to be an effective risk stratification tool in many surgical settings. It
Michalik, Cyprian, Juszczak, Kajetan, Stelmach, Andrzej, Kenig, Jakub, Drewa, Tomasz   +4 more
openaire   +2 more sources

Barnes Hospital Bulletin [PDF]

, 1986
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1246/thumbnail ...

core   +1 more source