Isolation and Characterization of a Rhodobacter Capsulatus hemC Mutant. [PDF]
, 2001 Rhodobacter capsulatus, a purple, nonsulfur photosynthetic bacterium, uses the tetrapyrrole pathway to synthesize four end products: heme, bacteriochlorophyll, vitamin B12, and siroheme. This laboratory has focused on the regulation of the common pathway
Sullivan, Karen Coleman
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Photochemistry and Photobiology, Volume 100, Issue 6, Page 1541-1560, November/December 2024.Photodynamic therapy (PDT) is now popular for treating nonmelanoma skin cancer (NMSC), but can be ineffective for larger skin tumors, mainly due to inadequate production of PpIX. Work over the past two decades has shown that differentiation‐promoting agents, including methotrexate, 5‐fluorouracil and vitamin D can be combined with ALA‐PDT as ...
Sanjay Anand +2 more
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Sister Dehalobacter Genomes Reveal Specialization in Organohalide Respiration and Recent Strain Differentiation Likely Driven by Chlorinated Substrates [PDF]
, 2016 The genomes of two closely related Dehalobacter strains (strain CF and strain DCA) were assembled from the metagenome of an anaerobic enrichment culture that reductively dechlorinates chloroform (CF), 1,1,1-trichloroethane (1,1,1-TCA) and 1,1 ...
Elizabeth A. Edwards +4 more
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Metabolic Engineering of Saccharomyces cerevisiae for Fermentative Production of Heme
Biotechnology Journal, Volume 19, Issue 10, October 2024.Graphical Abstract and Lay Summary Heme is a key ingredient required to mimic the color and flavor of meat in plant‐based alternatives. Herein, the efficient synthesis of heme was achieved by reconstructing the heme biosynthetic pathway in S. cerevisiae.
Hyun‐Jae Lee +4 more
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Photodynamic inactivation of red cell uroporphyrinogen decarboxylase by porphyrins
International Journal of Biochemistry, 1986 Les effets de la lumière et des porphyrines sur l'activité de l'uroporphyrinogène décarboxylase érythrocytaire ont été étudiés. La photoinactivation de l'uroporphyrinogène décarboxylase dépend de la concentration d'uroporphyrine, du temps d'irradiation et de la température.
Alcira Batlle +4 more
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Hepatitis C virus syndrome: A constellation of organ- and non-organ specific autoimmune disorders, B-cell non-Hodgkin's lymphoma, and cancer [PDF]
, 2015 The clinical course of chronic hepatitis C virus (HCV) infection is characterized by possible development of both liver and extrahepatic disorders. The tropism of HCV for the lymphoid tissue is responsible for several immune-mediated disorders; a poly ...
Antonelli, Alessandro +7 more
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Iron Necessity: The Secret of Wolbachia's Success? [PDF]
, 2014 The bacterium Wolbachia (order Rickettsiales) is probably the world's most successful vertically-transmitted symbiont, distributed among a staggering 40% of terrestrial arthropod species. Wolbachia has great potential in vector control due to its ability
Darby, Alistair C +2 more
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Action of uroporphyrinogen decarboxylase on uroporphyrinogen III [PDF]
Biochemical Journal, 1991 J L, Luo, C K, Lim
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Stukturelle und Biochemische Untersuchungen zweier Enzyme des Tetrapyrrol Stoffwechsels [PDF]
, 2007 The complex enzymatic catalysis involved in the forked tetrapyrrole biosynthesis is slowly becoming unravelled. During the last decades, work done on the biochemical and structural fields has contribute to the current knowledge about its several ...
Pereira Martins, Berta Maria Dias
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Uneven distribution of cobamide biosynthesis and dependence in bacteria predicted by comparative genomics. [PDF]
, 2019 The vitamin B12 family of cofactors known as cobamides are essential for a variety of microbial metabolisms. We used comparative genomics of 11,000 bacterial species to analyze the extent and distribution of cobamide production and use across bacteria ...
Haft, David R +6 more
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