Results 121 to 130 of about 5,145,076 (274)

The State of Knowledge of the Primary and Secondary Metabolites of the Iris Genus

open access: yesChemistry &Biodiversity, Volume 23, Issue 1, January 2026.
The genus Iris L. (Iridaceae) comprises over 320 species, primarily found in the northern hemisphere. Iris species are important in horticulture, folklore and medicine, and contain a variety of primary and secondary metabolites with significant biological activity.
Olha Mykhailenko   +3 more
wiley   +1 more source

Bioactive Potential of Origanum vulgare Rhizomes: Phenolic Composition, Antioxidant, Antibacterial, and Cytotoxicity Profiles

open access: yesFood Science &Nutrition, Volume 14, Issue 1, January 2026.
Oregano rhizomes, often treated as waste, contain valuable bioactive compounds, highlighting their sustainable potential. LC–MS/MS‐DAD analysis identified 14 phenolic compounds, with salvianolic acid A unique to rhizomes. Rhizome water extracts showed strong antioxidant activity and notable antimicrobial effects, effectively inhibiting MRSA and MSSA ...
Elena Kurin   +11 more
wiley   +1 more source

Effects of Ursolic Acid on Colorectal Cancer: A Review of Recent Evidence

open access: yesNutraceuticals
Colorectal cancer is the third leading cause of cancer-related deaths, and the five-year survival rate of the metastatic disease is less than 15%. Treatment approaches include surgery, systemic chemotherapy and radiotherapy. The aggressive nature and low
Amanda Kornel, Evangelia Tsiani
doaj   +1 more source

Chemical Constituents of Hedyotis dichotoma and their Biological Activity [PDF]

open access: yes, 1996
Two compounds, isovitexin and ursolic acid, were isolated from the aerial parts of Hedyotis dichotoma. Anti-microbial assays indicated that isovitexin was active against fungus and candida.
Aimi, Norio   +3 more
core  

Betulinic Acid Suppresses UBE2T Expression via MAPK/ERK Inhibition to Block FANCI and FANCD2 Monoubiquitination in Glioblastoma

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 1, January 2026.
ABSTRACT Platinum‐based chemotherapy remains a cornerstone of glioma treatment, yet resistance driven by the Fanconi anaemia (FA) DNA repair pathway limits efficacy. Here, we identified betulinic acid (BA) as a potent inhibitor of FA pathway activation.
Yifeng Bao, Maode Wang
wiley   +1 more source

Preparation, characterization and evaluation of the in vivo trypanocidal activity of ursolic acid-loaded solid dispersion with poloxamer 407 and sodium caprate

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2015
Ursolic acid is a promising candidate for treatment of Chagas disease; however it has low aqueous solubility and intestinal absorption, which are both limiting factors for bioavailability. Among the strategies to enhance the solubility and dissolution of
Josimar Oliveira Eloy   +3 more
doaj   +1 more source

Ursolic Acid and Its Derivatives as Bioactive Agents

open access: yesMolecules, 2019
Non-communicable diseases (NCDs) such as cancer, diabetes, and chronic respiratory and cardiovascular diseases continue to be threatening and deadly to human kind.
Sithenkosi Mlala   +3 more
semanticscholar   +1 more source

Chemical composition and water permeability of fruit and leaf cuticles of Olea europaea L. [PDF]

open access: yes, 2017
The plant cuticle, protecting against uncontrolled water loss, covers olive (Olea europaea) fruits and leaves. The present study describes the organ-specific chemical composition of the cuticular waxes and the cutin and compares three developmental ...
Burghardt, Markus   +5 more
core   +2 more sources

Variation in the impact of stem scar and cuticle on water loss in highbush blueberry fruit argue for the use of water permeance as a selection criterion in breeding [PDF]

open access: yes, 2017
The role of fruit scar on water loss from fresh harvested, fully blue highbush blueberry (Vaccinium corymbosum L.) fruit was studied on three germplasm lines from each of three half-sib families at University of Talca, Chile. The stem scar of half of the
Beaudry, Randolph M.   +3 more
core   +2 more sources

Therapeutic effect of Melissa officinalis in an amyloid-β rat model of Alzheimer’s disease [PDF]

open access: yes, 2018
Introduction: Medicinal herbs have several components with different pharmacological effects. It has been described that Melissa officinalis is able to improve memory in different models of learning.
Beheshti, Siamak., Shahmoradi, Bahareh.
core   +2 more sources

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