Results 101 to 110 of about 51,027,052 (360)

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

Usability as a Dominant Quality Attribute [PDF]

open access: yesarXiv, 2015
Whenever an architect or a team of architects begins an architectural design, there are certain goals set to achieve. There are many factors involved in setting up goals for the architecture design such as type of the project, end user perspective, functional and non-functional requirements and so on.
arxiv  

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Does GenAI Make Usability Testing Obsolete? [PDF]

open access: yesarXiv
Ensuring usability is crucial for the success of mobile apps. Usability issues can compromise user experience and negatively impact the perceived app quality. This paper presents UX-LLM, a novel tool powered by a Large Vision-Language Model that predicts usability issues in iOS apps.
arxiv  

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale   +9 more
wiley   +1 more source

Enabling the Usability Heuristics of Agile Base Systems to Improve Quality of Local Software Industry

open access: yesMehran University Research Journal of Engineering and Technology, 2019
Many agile software development practices are promoted to improve the quality of software products. In recent years agile software development overlooked the usability features that effected system productivity.Usability is a main feature of interaction.
Kiran Saeed   +4 more
doaj  

Usable-by-Construction: a formal framework [PDF]

open access: yesarXiv
We propose here to look at how abstract a model of a usable system can be, but still say something useful and interesting, so this paper is an exercise in abstraction and formalisation, with usability-of-design as an example target use. We take the view that when we claim to be designing a usable system we have, at the very least, to give assurances ...
arxiv  

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

Usability Engineering in Industrial Practice [PDF]

open access: yes, 1997
Do developers use proven usability techniques like user involvement, usability testing, and iterative design in industrial practice? Based on inside knowledge of many different types of projects, the author must conclude that these techniques are seldom used. There are several reasons for that. For instance: (1) The market pressure is not there.
openaire   +2 more sources

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