Results 251 to 260 of about 51,027,052 (360)

A Health Evaluation Method of AMHTS Examinees by Using Knowledge Engineering

, 1988
稲田 紘, 吉川 博通, 杉本 敞一, 武田 裕, 通敏 井上, 福島 正勝, 吉田 途男, 阿部 裕   +7 more
openalex   +2 more sources

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

V3+ extends the V3 framework to ensure user-centricity and scalability of sensor-based digital health technologies. [PDF]

NPJ Digit Med
Bakker JP, Barge R, Centra J, Cobb B, Cota C, Guo CC, Hartog B, Horowicz-Mehler N, Izmailova ES, Manyakov NV, McClenahan S, Motola S, Patel S, Paun O, Schoone M, Sezgin E, Switzer T, Tandon A, van den Brink W, Vairavan S, Vandendriessche B, Vrijens B, Goldsack JC.   +22 more
europepmc   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

A Usability Pilot Study of a Sensor-Guided Interactive System for Dexterity Training in Parkinson's Disease. [PDF]

Sensors (Basel)
Krummenacher N, Gerber SM, Pastore-Wapp M, Single M, Bohlhalter S, Nef T, Vanbellingen T.   +6 more
europepmc   +1 more source

Studies on the Genome Engineering Using Bacillus subtilis 168.

, 1994
Mitsuhiro Itaya
openalex   +2 more sources

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Digital Health Intervention for Patient Monitoring in Immune-Mediated Inflammatory Diseases: Cocreation and Feasibility Study of the IMIDoc Platform.

JMIR Hum Factors
Benavent D, Iniesta-Chamorro JM, Novella-Navarro M, Pérez-Martínez M, Martínez-Sánchez N, Kaffati M, Juárez-García M, Molinari-Pérez M, González-Torbay A, Gutiérrez M, López-Juanes N, Navarro-Compán V, Monjo-Henry I, Rodríguez-Rosales G, Bachiller J, Calvo-Aranda E, Michelena X, Berbel-Arcobé L, Balsa A, IMIDOC Research Team, Gómez EJ, Plasencia-Rodríguez C.   +21 more
europepmc   +1 more source

Feasibility and preliminary effects of an app-based physical activity intervention for individuals with depression (MoodMover): A protocol for a single-arm, pre-post intervention study. [PDF]

PLoS One
Tang Y, Gierc M, La H, Liu S, Lam RW, Puterman E, Faulkner G.   +6 more
europepmc   +1 more source

Mapping Hsp104 interactions using cross‐linking mass spectrometry

FEBS Open Bio, EarlyView.
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal, Karolina Michalska, Andrzej Joachimiak, Lukasz A. Joachimiak   +3 more
wiley   +1 more source