Results 101 to 110 of about 108,976 (263)

Methodological Quality of User-Centered Usability Evaluation of Digital Applications to Promote Citizens’ Engagement and Participation in Public Governance: A Systematic Literature Review

Digital
This systematic literature review aimed to assess the methodological quality of user-centered usability evaluation of digital applications to promote citizens’ engagement and participation in public governance by (i) systematizing their purposes; (ii ...
Rute Bastardo, João Pavão, Nelson Pacheco Rocha   +2 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

A mixed-methods evaluation framework for electronic health records usability studies. [PDF]

J Biomed Inform, 2019
Khairat S, Coleman C, Newlin T, Rand V, Ottmar P, Bice T, Carson SS.   +6 more
europepmc   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

A Systematic Review of 10 Years of Augmented Reality Usability Studies: 2005 to 2014. [PDF]

Front Robot AI, 2018
Dey A, Billinghurst M, Lindeman RW, Swan JE.   +3 more
europepmc   +1 more source

Usability Studie IREON

, 2008
Der Umgang mit einer Digitalen Bibliothek ist vom Anwendungszusammenhang abhängig. Diese Arbeit zeigt anhand von IREON - Fachportal Internationale Beziehungen und Länderkunde, dass die Kulturanthropologie empirische Ansätze mit einer wohlbegründeten Methodik bietet, um variable Nutzungskontexte zu analysieren und zu interpretieren.
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Avaluació de la usabilitat en catàlegs centrats en l'usuari : una proposta basada en heurístiques

BiD: Textos Universitaris de Biblioteconomia i Documentació, 2016
Objectiu: analitzar els catàlegs actuals centrats en l'usuari i les eines de descobriment implementats a les biblioteques universitàries des del punt de vista de la usabilitat a partir d'una proposta específica basada en heurístiques.
Muñoz Egido, Daniel, Hernández Pérez, Tony   +1 more
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source