Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Psychometric evaluation of the Spanish-language version of the health information technology usability evaluation scale (Health-ITUES). [PDF]
Gerchow L, Schnall R, Liu J.
europepmc +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and content of health facility routine data recording and reporting forms for maternal, newborn, and child health: a scoping review of literature. [PDF]
Peeler A +9 more
europepmc +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Design and impact of gamification, theory-driven frameworks, and human-centered design in mobile health applications for preconception care: A systematic review protocol. [PDF]
Muhamad Rusdi NDS +3 more
europepmc +1 more source
This report will summarize the feedback of the feasibility study, where 20 users (4 per pilot) will be provided with the CAREGIVERSPRO-MMD platform. They will be instructed on how to use the platform (as in normal pilot operation) but no previous assessment will be done and no data will be recorded from them except from the usability related data.
openaire +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Development and usability evaluation of HOPE: A patient-centered mHealth application for HTN self-management in Iran. [PDF]
Hayavi-Haghighi MH +3 more
europepmc +1 more source

