Results 91 to 100 of about 2,754,892 (246)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Examining Correlations in Usability Data to Effectivize Usability Testing [PDF]

open access: yese-Informatica Software Engineering Journal, 2011
Hinely Mark, Winter Jeff
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

How UX Practitioners Produce Findings in Usability Testing [PDF]

open access: yes, 2019
Usability testing has long been a core interest of HCI research and forms a key element of industry practice. Yet our knowledge of it harbours striking absences.
Reeves, Stuart
core   +1 more source

USABILITY TESTING SISTEM PADA E-ACADEMIC POLITEKNIK HARAPAN BERSAMA

open access: yesEmitor: Jurnal Teknik Elektro, 2016
Layanan publik yang berbasiskan web saat ini sudah menjadi bagian yang sangat penting dalam menunjang keberhasilan dari suatu instansi pendidikan,  akan tetapi layanan yang berbasiskan web masih banyak yang kesulitan dalam menggunakannya, bahkan tidak ...
Dega Surono Wibowo
doaj  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Scoping analytical usability evaluation methods: A case study [PDF]

open access: yes, 2008
Analytical usability evaluation methods (UEMs) can complement empirical evaluation of systems: for example, they can often be used earlier in design and can provide accounts of why users might experience difficulties, as well as what those difficulties ...
Thomas Green   +7 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Emotion Recognition in Usability Testing: A Framework for Improving Web Application UI Design

open access: yesApplied Sciences
Traditional usability testing methods often lack the ability to fully capture different aspects of the user experience (UX). The focus of this research work is to propose a framework and develop its comprehensive prototype to improve usability testing ...
Darius Drungilas   +2 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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