Results 141 to 150 of about 2,754,892 (246)

Feasibility of the "OA Coach" Mobile App to Support Individuals with Osteoarthritis: Development and Usability Testing. [PDF]

JMIR Hum Factors
Duong V, Bloul N, Bowden J, Bracken K, Bryce K, Deveza L, Eyles J, Farivar A, Huang R, Kobayashi S, Liu N, Pratt C, Strong C, Venkatesha V, Yu S, Hunter DJ.   +15 more
europepmc   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Co-Creation and Usability Testing of a Digital Cardiac Rehabilitation Program (eCardiacRehab): Design and Development Study. [PDF]

JMIR Cardio
Nordfonn OK, Johnsen Ramstad K, Roed Pettersen T, Hjertvikrem N, Aamot Aksetøy IL, Agcaoili Borge AJ, Gerdts E, Hesthammer JG, Hole T, Instenes I, Isaksen A, Krumsvik OA, Landaas M, Moltu C, Rotevatn S, Schjøtt J, Sommersten CH, Tryti JO, Norekvål TM.   +18 more
europepmc   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

How to Conduct Usability Testing of Medical Education Simulations: Methods Tutorial Using a Telemedicine Simulation for Maternal Care. [PDF]

JMIR Med Educ
Lesselroth BJ, Douglas A, Monkman H, Marcilly R, Bellavia K, Anderson M, Van Buren J, Parsons C, Mohanty S, Homco J, Richards M, Gold KP.   +11 more
europepmc   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Translation Validation, Software Adaptation, and Usability Testing of a Spanish Contraception Decision Tool: Protocol for a Mixed Methods Pilot Study. [PDF]

JMIR Res Protoc
Kang MM, Perez A, Brooks-Greisen A, Burgos D, Barrios R, Fermin Olivares DV, Perez Mukdsi A, Llanes M, Van Sparrentak M, Wynn C, Wu JP.   +10 more
europepmc   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Inclusive design in digital mental health: stakeholders with disabilities must be central to usability testing. [PDF]

Front Digit Health
Tranter H, Giles N, Price T, Stockton-Powdrell C, Foster S, Alam S, Hassan L, Edbrooke Childs J, Chmielowska M, Vines Booth M, Abel KM, Whelan P.   +11 more
europepmc   +1 more source