Results 201 to 210 of about 36,051,626 (291)

Vasopressor Use in Acute Burn Resuscitation: A Retrospective Study. [PDF]

Acta Anaesthesiol Scand
Knappskog K, Botnar K, Kleinhapl J, Song J, El Ayadi A, Onarheim H, Guttormsen AB, Golovko G, Wolf S, Almeland SK.   +9 more
europepmc   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Factors associated with adolescent use of tobacco products in the Upper East Region of Ghana: A cross-sectional study. [PDF]

Tob Induc Dis
Logo DD, Kodali PB, Anaman-Torgbor J, Chaffee BW, Ling PM, Bialous S, Owusu-Dabo E.   +6 more
europepmc   +1 more source

Antilymphocyte globulins-clinical use [PDF]

, 1968
Porter, KA, Starzl, TE
core  

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

The Association Between Cannabis Use and Electrocardiographic Abnormalities in People Living With HIV. [PDF]

J Acquir Immune Defic Syndr
Larson ME, Pan Y, Lakhani F, Chavez JV, Santana A, Nogueira NF, Lieberman A, Riley ED, Wu KC, Tien P, Kizer J, Floris-Moore M, Pyslar N, Palella FJ, Witt MD, Magnani JW, Plankey M, Lazar J, Sharma A, Moran C, Topper E, Fox E, Kambrakos L, Fischl M, Jones DL, Alcaide ML, Vidot D, Martinez C.   +27 more
europepmc   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Understanding opioid use within the substance use journeys of adults receiving treatment: a qualitative study protocol of the participant-led timeline mapping approach. [PDF]

BMJ Open
Estrella MJ, Wells S, Foy R, Quilty L, Bozinoff N, Buckley L, Lincoln S, Patenaude S, Ali F.   +8 more
europepmc   +1 more source