Results 201 to 210 of about 2,269,689 (267)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Does Reducing the Size of the Tobacco Power Wall Affect Young People's Risk of Future Use of Tobacco Products? An Experimental Investigation. [PDF]

J Stud Alcohol Drugs
Martino SC, Setodji CM, Dunbar MS, Jenson D, Wong JCS, Torbatian A, Shadel WG.   +6 more
europepmc   +1 more source

Implementation of Quitline Financial Incentives to Increase Counseling Sessions Among Adults Who Use Menthol Tobacco Products. [PDF]

Health Promot Pract
Bourne DE, Williams R, Osbahr L, Roemhildt M, Villanti AC.   +4 more
europepmc   +1 more source

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Measuring a product’s usefulness

WORK: A Journal of Prevention, Assessment & Rehabilitation, 2012
This paper explains how a product’s usefulness may be defined and measured. Many aspects of consumer product assessments are conducted sub-consciously and this process is closely examined. A product’s usefulness can be evaluated by measuring its advantages over alternative solutions based on specific criteria associated with fundamentals needs.
Francois, Aubin, Hasmik, Atoyan, Jean-Marc, Robert, Tigran, Atoyan   +3 more
openaire   +3 more sources

Coagulation products and their uses

American Journal of Health-System Pharmacy, 2000
The indications, pharmacokinetics, and therapeutic guidelines for available coagulation products are reviewed. Patients with hemophilia, von Willebrand's disease (VWD), or acquired inhibitors to antihemophilic factor (AHF) cannot spontaneously stop an acute hemorrhage.
S S, Shord, C M, Lindley
openaire   +2 more sources

Using Cartesian Product for Animation

The Journal of Visualization and Computer Animation, 2000
AbstractIn the field of geometric modelling for animation, 4D modelling (time being the fourth dimension) seems to be a natural extension of 3D modelling. But time dimension is not easy to apprehend and 4D objects are difficult to interpret and to control in general.
Xavier Skapin, Pascal Lienhardt
openaire   +2 more sources

Spillover effects of production of IT on use of IT

36th Annual Hawaii International Conference on System Sciences, 2003. Proceedings of the, 2003
We analyse new data on the production and use of IT around the world to assess the impact of changes in IT production in the 1990s on economic development. We provide empirical evidence on a fundamental question: Besides the direct effect on GDP, does an emphasis on IT production have a spillover effect on the level of IT diffusion?
Dale Ganley, Kenneth L. Kraemer, Poh-Kam Wong   +2 more
openaire   +1 more source