Results 81 to 90 of about 2,269,689 (267)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Production and characterization of L-asparaginase by Aspergillus niger: A sustainable use of pitaya (Hylocereus spp.) by-products

Sustainable Chemistry for the Environment
The present study focused on the optimization of the L-asparaginase production by solid-state fermentation from Aspergillus niger INCQS 40018 (ATCC 1004) using pitaya by-product and the determination of its biochemical characterization.
John Nonvignon Bossis Honfoga, Priscilla Amaral Nascimento, Alexsandra Nascimento Ferreira, Emília Carmem da Silva, Luciana Carolina Bauer, Jabson Meneses Teixeira, Nívio Batista Santana, Renata Cristina Ferreira Bonomo   +7 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

On the Production of Useful Knowledge [PDF]

The Milbank Quarterly, 2017
openaire   +2 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Toward Sustainable Fertilizer Use: Fundamental Analysis of Ashes from Bamboo By-Products

BioResources
Bamboo is increasingly recognized as a sustainable biomass resource, supporting the global transition toward renewable raw materials for construction, landscaping, pulp and cellulose production, and high-performance bio-composites.
Ji-Yeon Sim, Yong-Hui Choi, Byeongho Kim, Se-Yeong Park   +3 more
doaj  

Use of Liquid Industrial By-Products as Biostimulants in the Remediation of Hydrocarbon-Contaminated Soils

Clean Technologies
Soil contamination by petroleum hydrocarbons represents a significant environmental challenge, especially in industrial and urban areas. This study evaluates the use of three industrial liquid by-products—sludge dewatering sidestream (SD), leftover yeast
Emilio Ritoré, Carmen Arnaiz, José Morillo, Agata Egea-Corbacho, José Usero   +4 more
doaj   +1 more source

Leaf Protein: Production and Use

Interdisciplinary Science Reviews, 1990
AbstractProtein extracted from leafy crops is potentially the most abundant protein concentrate. It is an acceptable complement to green vegetables cooked in the normal manner, and it replaces oil-seed products and fishmeal in animal feeds. It is so easy to make, and its value as a source of protein and vitamin A is so obvious in human feeding trials ...
openaire   +1 more source