Results 101 to 110 of about 700,482 (307)

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Inpatient Outsourced Dialysis: Scorecards Usefulness and Usability for Monitoring Patient Safety [poster]

open access: yes, 2019
Background: Dialysis services are expected to meet quality metrics as conditions of coverage for The Joint Commission. The use of scorecards improved the ability to monitor quality in areas for infection prevention and safety.
Wendl, Stephanie
core  

Adapting tam and ECT: continuance intention of e-shopping in Saudi Arabia [PDF]

open access: yes, 2010
The objective of this study is to clarify the theoretical problem and identify factors that could explain the level of continuance intention of e-shopping in context of Saudi Arabia.
Dennis, C   +3 more
core  

What’s the Use? On the Uses of Use

open access: yesNORA - Nordic Journal of Feminist and Gender Research, 2022
  +4 more sources

Judgmental evaluation of the CEFR by stakeholders in language testing

open access: yesRevista de Lingüística y Lenguas Aplicadas, 2015
This study provides insights into the judgmental evaluation of the Common European Framework of Reference for Languages (CEFR) by stakeholders or users.
Mathea Simons, Jozef Colpaert
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Inpatient Outsourced Dialysis: Scorecards Usefulness and Usability for Monitoring Patient Safety [paper]

open access: yes, 2019
Background: Dialysis services are expected to meet quality metrics as conditions of coverage for The Joint Commission. The use of scorecards improved the ability to monitor quality in areas for infection prevention and safety.
Wendl, Stephanie
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy