Results 211 to 220 of about 463,209 (335)

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

User-Centered Design and Reference Services in International Librarianship: A Case Study of Nazarbayev University Library

, 2013
Elizabeth A. King, Heidi Dowding, Julia T. Pflager   +2 more
openalex   +2 more sources

User-Centered Design Practices in Digital Humanities – Experiences from DARIAH and CENDARI [PDF]

, 2017
Klaus Thoden, Juliane Stiller, Nataša Bulatović, Hanna-Lena Meiners, Nadia Boukhelifa   +4 more
openalex   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Designing Values Elicitation Technologies for Mental Health and Chronic Care Integration: User-Centered Design Approach. [PDF]

JMIR Form Res
Rooper IR, Liem WW, Burla M, Gordon J, Baez LM, Kornfield R, Berry ABL.   +6 more
europepmc   +1 more source

A Survey of User-Centered System Design for Supporting Online Collaborative Writing

, 2013
Nani Sri Handayani
openalex   +2 more sources

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Corrigendum to "The User-Centered Design of a Clinical Dashboard and Patient-Facing App for Gestational Diabetes". [PDF]

J Diabetes Sci Technol
europepmc   +1 more source

Supporting the uninitiated in user-centered design

, 2014
Maria Ralph, Petra Björndal
openalex   +1 more source

User-Centered Design of a Portable Fire Extinguisher [PDF]

, 2017
Mary Amos, Glyn Lawson
openalex   +1 more source