Results 271 to 280 of about 518,430 (330)

An Attempt to Fathom the Role of Annotations in User-Centered Design Process

, 2019
Jean-Luc Hak, Olivier Nicolas, Marco Winckler, Philippe Palanque   +3 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Development of a Predictive Dashboard With Prescriptive Decision Support for Falls Prevention in Residential Aged Care: User-Centered Design Approach. [PDF]

JMIR Aging
Silva SSM, Wabe N, Nguyen AD, Seaman K, Huang G, Dodds L, Meulenbroeks I, Mercado CI, Westbrook JI.   +8 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Employing user-centered design to develop a remote technology kit for studying young children's social communication skills. [PDF]

J Pediatr Psychol
Petruccelli M, Howard M, Morelos A, Wainer A, Broder-Fingert S, Ingersoll B, Stone WL, Carter AS.   +7 more
europepmc   +1 more source

Desain UI/UX Mobile App mengenai Pengelolaan Konten dengan Search Engine Optimization menggunakan Pendekatan User Centered Design

Rian Farta Wijaya, Randi Rian Putra
openalex   +2 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

A Smart Glass Telemedicine Application for Prehospital Communication: User-Centered Design Study.

J Med Internet Res
Zhang Z, Bai E, Xu Y, Stepanian A, Kutzin JM, Adelgais K, Ozkaynak M.   +6 more
europepmc   +1 more source

Addressing the "Black Hole" of Low Back Pain Care With Clinical Decision Support: User-Centered Design and Initial Usability Study. [PDF]

JMIR Form Res
Rudin RS, Herman PM, Vining R.
europepmc   +1 more source

An Approach to Assist the Design of User-Centered Solutions based on Generative AI

Thiago Alves de Queiroz, Gretchen Macedo, Igor Steinmacher, Tayana Conte, Ana Carolina Oran, Bruno Gadelha   +5 more
openalex   +2 more sources